Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2022 Apr;2(2):14.
doi: 10.20517/jca.2021.38. Epub 2022 Jan 18.

Thermophiles reveal the clues to longevity: precise protein synthesis

Affiliations
Comment

Thermophiles reveal the clues to longevity: precise protein synthesis

Manisha Deogharia et al. J Cardiovasc Aging. 2022 Apr.

Abstract

PubMed Disclaimer

Conflict of interest statement

Conflicts of interest Both authors declared that there are no conflicts of interest.

Comment on

  • Increased fidelity of protein synthesis extends lifespan.
    Martinez-Miguel VE, Lujan C, Espie-Caullet T, Martinez-Martinez D, Moore S, Backes C, Gonzalez S, Galimov ER, Brown AEX, Halic M, Tomita K, Rallis C, von der Haar T, Cabreiro F, Bjedov I. Martinez-Miguel VE, et al. Cell Metab. 2021 Nov 2;33(11):2288-2300.e12. doi: 10.1016/j.cmet.2021.08.017. Epub 2021 Sep 14. Cell Metab. 2021. PMID: 34525330 Free PMC article.

References

    1. Martinez-Miguel VE, Lujan C, Espie-Caullet T, et al. Increased fidelity of protein synthesis extends lifespan. Cell Metab 2021;33:2288–300.e12. - PMC - PubMed
    1. Campisi J, Kapahi P, Lithgow GJ, Melov S, Newman JC, Verdin E. From discoveries in ageing research to therapeutics for healthy ageing. Nature 2019;571:183–92. - PMC - PubMed
    1. Kaushik S, Cuervo AM. Proteostasis and aging. Nat Med 2015;21:1406–15. - PubMed
    1. Verma K, Verma M, Chaphalkar A, Chakraborty K. Recent advances in understanding the role of proteostasis. Fac Rev 2021;10:72. - PMC - PubMed
    1. Syntichaki P, Troulinaki K, Tavernarakis N. eIF4E function in somatic cells modulates ageing in Caenorhabditis elegans. Nature 2007;445:922–6. - PubMed

LinkOut - more resources