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Comment
. 2023 Mar;24(3):387-388.
doi: 10.1038/s41590-023-01429-w.

γδ T cells maintain sensitivity to immunotherapy in MHC-I-deficient tumors

Bruno Silva-Santos  1 , Sofia Mensurado  2
Affiliations
Comment

γδ T cells maintain sensitivity to immunotherapy in MHC-I-deficient tumors

Bruno Silva-Santos et al. Nat Immunol. 2023 Mar.
No abstract available

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Comment on

  • γδ T cells are effectors of immunotherapy in cancers with HLA class I defects.
    de Vries NL, van de Haar J, Veninga V, Chalabi M, Ijsselsteijn ME, van der Ploeg M, van den Bulk J, Ruano D, van den Berg JG, Haanen JB, Zeverijn LJ, Geurts BS, de Wit GF, Battaglia TW, Gelderblom H, Verheul HMW, Schumacher TN, Wessels LFA, Koning F, de Miranda NFCC, Voest EE. de Vries NL, et al. Nature. 2023 Jan;613(7945):743-750. doi: 10.1038/s41586-022-05593-1. Epub 2023 Jan 11. Nature. 2023. PMID: 36631610 Free PMC article.

References

    1. Ijsselsteijn, M. E. et al. Br. J. Cancer 120, 815–818 (2019). - DOI - PubMed - PMC
    1. de Vries, N. L. et al. Nature https://doi.org/10.1038/s41586-022-05593-1 (2023). - DOI - PubMed - PMC
    1. Nishino, M. et al. Nat. Rev. Clin. Oncol. 14, 655–668 (2017). - DOI - PubMed - PMC
    1. Silva-Santos, B., Mensurado, S. & Coffelt, S. B. Nat. Rev. Cancer 19, 392–404 (2019). - DOI - PubMed
    1. Mikulak, J. et al. JCI Insight 4, 125884 (2019). - DOI - PubMed

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