Association between self-reported sedentary behavior and health-related quality of life among infertile women with polycystic ovary syndrome

doi:10.1186/s12905-023-02222-5

. 2023 Feb 14;23(1):67.

doi: 10.1186/s12905-023-02222-5.

Association between self-reported sedentary behavior and health-related quality of life among infertile women with polycystic ovary syndrome

Yanjun Cao¹, Guopeng Li², Yanbei Ren³

Affiliations

¹ Department of Neurology, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, People's Republic of China.
² Department of Health Psychology, School of Nursing and Rehabilitation, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, People's Republic of China.
³ Department of Cardiology, Qilu Hospital of Shandong University, Jinan, 250012, Shandong, People's Republic of China. renyanbei0104@126.com.

PMID: 36788488
PMCID: PMC9926864
DOI: 10.1186/s12905-023-02222-5

Association between self-reported sedentary behavior and health-related quality of life among infertile women with polycystic ovary syndrome

Yanjun Cao et al. BMC Womens Health. 2023.

. 2023 Feb 14;23(1):67.

doi: 10.1186/s12905-023-02222-5.

Authors

Yanjun Cao¹, Guopeng Li², Yanbei Ren³

Affiliations

¹ Department of Neurology, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, People's Republic of China.
² Department of Health Psychology, School of Nursing and Rehabilitation, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, People's Republic of China.
³ Department of Cardiology, Qilu Hospital of Shandong University, Jinan, 250012, Shandong, People's Republic of China. renyanbei0104@126.com.

PMID: 36788488
PMCID: PMC9926864
DOI: 10.1186/s12905-023-02222-5

Abstract

Background: High sedentary behavior and poor health-related quality of life (HRQoL) were common among women with polycystic ovary syndrome (PCOS). However, the association of sedentary behavior with HRQoL among infertile women with PCOS is still unknown. This study aimed to investigate the association of sedentary behavior with HRQoL among them.

Methods: A cross-sectional study was conducted with 283 participants recruited from infertility outpatient clinic. A self-administered, structured questionnaire including the modified PCOS health-related QoL questionnaire (MPCOSQ), the International Physical Activity Questionnaire short form (IPAQ-SF), the Patient Health Questionnaire-9 (PHQ-9), and the Generalized Anxiety Disorder-7 (GAD-7) was used. Anthropometric and laboratory indictors related to PCOS were also collected. Multivariable linear regression analyses were performed to identify the associations. Bonferroni correction was utilized for multiple testing correction.

Results: Sedentary behavior was associated with reduced HRQoL among this group. Specifically, over seven hours per day of sedentary behavior was strongly associated with total and several aspects of HRQoL (β ranged from - 0.378 to - 0.141, all P < 0.0063) after adjusting for physical activity, anxiety and depression. In addition, elevated BMI (β = - 0.407, P < 0.001) and anxiety (β ranged from - 0.410 to - 0.245, all P < 0.0063) were associated with poor HRQoL, while physical activity and depression were not.

Conclusion: Sedentary behavior is an important behavior among infertile women with PCOS as it was associated with poorer HRQoL. Future interventions seeking to improve HRQoL should be considered to reduce sedentary behavior and psychological burden as primary intervention targets.

Keywords: Anxiety; Depression; Physical activity; Polycystic ovary syndrome; Quality of life; Sedentary behavior.

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Conflict of interest statement

The authors declare that they have no competing interests.

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References

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1. Lizneva D, Suturina L, Walker W, Brakta S, Gavrilova-Jordan L, Azziz R. Criteria, prevalence, and phenotypes of polycystic ovary syndrome. Fertil Steril. 2016;106(1):6–15. doi: 10.1016/j.fertnstert.2016.05.003. - DOI - PubMed
1. Teede HJ, Misso ML, Costello MF, Dokras A, Laven J, Moran L, Piltonen T, Norman RJ. Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome. Human Reprod (Oxford, England) 2018;33(9):1602–1618. doi: 10.1093/humrep/dey256. - DOI - PMC - PubMed
1. Giampaolino P, Foreste V, Di Filippo C, Gallo A, Mercorio A, Serafino P, Improda FP, Verrazzo P, Zara G, Buonfantino C, et al. Microbiome and PCOS: state-of-art and future aspects. Int J Mol Sci. 2021;22(4):2048. doi: 10.3390/ijms22042048. - DOI - PMC - PubMed
1. Balen AH, Morley LC, Misso M, Franks S, Legro RS, Wijeyaratne CN, Stener-Victorin E, Fauser BC, Norman RJ, Teede H. The management of anovulatory infertility in women with polycystic ovary syndrome: an analysis of the evidence to support the development of global WHO guidance. Hum Reprod Update. 2016;22(6):687–708. doi: 10.1093/humupd/dmw025. - DOI - PubMed

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[1] Conway G, Dewailly D, Diamanti-Kandarakis E, Escobar-Morreale HF, Franks S, Gambineri A, Kelestimur F, Macut D, Micic D, Pasquali R, et al. The polycystic ovary syndrome: a position statement from the European Society of Endocrinology. Eur J Endocrinol. 2014;171(4):P1–29. doi: 10.1530/EJE-14-0253. - DOI - PubMed

[2] Conway G, Dewailly D, Diamanti-Kandarakis E, Escobar-Morreale HF, Franks S, Gambineri A, Kelestimur F, Macut D, Micic D, Pasquali R, et al. The polycystic ovary syndrome: a position statement from the European Society of Endocrinology. Eur J Endocrinol. 2014;171(4):P1–29. doi: 10.1530/EJE-14-0253. - DOI - PubMed

[3] Lizneva D, Suturina L, Walker W, Brakta S, Gavrilova-Jordan L, Azziz R. Criteria, prevalence, and phenotypes of polycystic ovary syndrome. Fertil Steril. 2016;106(1):6–15. doi: 10.1016/j.fertnstert.2016.05.003. - DOI - PubMed

[4] Lizneva D, Suturina L, Walker W, Brakta S, Gavrilova-Jordan L, Azziz R. Criteria, prevalence, and phenotypes of polycystic ovary syndrome. Fertil Steril. 2016;106(1):6–15. doi: 10.1016/j.fertnstert.2016.05.003. - DOI - PubMed

[5] Teede HJ, Misso ML, Costello MF, Dokras A, Laven J, Moran L, Piltonen T, Norman RJ. Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome. Human Reprod (Oxford, England) 2018;33(9):1602–1618. doi: 10.1093/humrep/dey256. - DOI - PMC - PubMed

[6] Teede HJ, Misso ML, Costello MF, Dokras A, Laven J, Moran L, Piltonen T, Norman RJ. Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome. Human Reprod (Oxford, England) 2018;33(9):1602–1618. doi: 10.1093/humrep/dey256. - DOI - PMC - PubMed

[7] Giampaolino P, Foreste V, Di Filippo C, Gallo A, Mercorio A, Serafino P, Improda FP, Verrazzo P, Zara G, Buonfantino C, et al. Microbiome and PCOS: state-of-art and future aspects. Int J Mol Sci. 2021;22(4):2048. doi: 10.3390/ijms22042048. - DOI - PMC - PubMed

[8] Giampaolino P, Foreste V, Di Filippo C, Gallo A, Mercorio A, Serafino P, Improda FP, Verrazzo P, Zara G, Buonfantino C, et al. Microbiome and PCOS: state-of-art and future aspects. Int J Mol Sci. 2021;22(4):2048. doi: 10.3390/ijms22042048. - DOI - PMC - PubMed

[9] Balen AH, Morley LC, Misso M, Franks S, Legro RS, Wijeyaratne CN, Stener-Victorin E, Fauser BC, Norman RJ, Teede H. The management of anovulatory infertility in women with polycystic ovary syndrome: an analysis of the evidence to support the development of global WHO guidance. Hum Reprod Update. 2016;22(6):687–708. doi: 10.1093/humupd/dmw025. - DOI - PubMed

[10] Balen AH, Morley LC, Misso M, Franks S, Legro RS, Wijeyaratne CN, Stener-Victorin E, Fauser BC, Norman RJ, Teede H. The management of anovulatory infertility in women with polycystic ovary syndrome: an analysis of the evidence to support the development of global WHO guidance. Hum Reprod Update. 2016;22(6):687–708. doi: 10.1093/humupd/dmw025. - DOI - PubMed

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Association between self-reported sedentary behavior and health-related quality of life among infertile women with polycystic ovary syndrome

Affiliations

Association between self-reported sedentary behavior and health-related quality of life among infertile women with polycystic ovary syndrome

Authors

Affiliations

Abstract

Conflict of interest statement

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Abstract

Conflict of interest statement

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