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Case Reports
. 2023 Jan 12;15(1):e33704.
doi: 10.7759/cureus.33704. eCollection 2023 Jan.

Removal of Polymer Clips From the Gallbladder Fossa in a Patient With Ehlers-Danlos Syndrome (EDS) to Treat Mast Cell Activation Syndrome (MCAS): A Case Report

Affiliations
Case Reports

Removal of Polymer Clips From the Gallbladder Fossa in a Patient With Ehlers-Danlos Syndrome (EDS) to Treat Mast Cell Activation Syndrome (MCAS): A Case Report

Yitong Xiao et al. Cureus. .

Abstract

Ehlers-Danlos syndrome (EDS) is a group of hereditary disorders characterized by fragility of connective tissue. Clinical manifestations of the disorder involve the skin, joints, blood vessels, and other internal organs. We report the case of a 29-year-old female suffering from EDS and mast cell activation syndrome (MCAS). Her history includes multiple orthopedic surgeries leading to the worsening of her symptoms. This was determined to be due to medical implants placed during her multiple procedures predisposing her to severe immunological reactions. This case report emphasizes the importance of meticulous surgical intervention when managing patients with EDS.

Keywords: ehlers-danlos syndrome; foreign body removal; hypersensitive reaction; mast cell activation syndrome; noninvasive surgery.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Three separate polymer Weck clips were removed from the gallbladder fossa.

References

    1. [Ehlers-Danlos syndrome] Leganger J, Søborg ML, Farholt S, Lund AM, Rosenberg J, Burcharth J. http://ugeskriftet.dk/videnskab/ehlers-danlos-syndrom Ugeskr Laeger. 2016;178:0. - PubMed
    1. Clinical and genetic aspects of Ehlers-Danlos syndrome, classic type. Malfait F, Wenstrup RJ, De Paepe A. Genet Med. 2010;12:597–605. - PubMed
    1. The multisystemic nature and natural history of joint hypermobility syndrome and Ehlers-Danlos syndrome in children: New research data conflict with widely held views. Grahame R. Rheumatology (Oxford) 2017;56:2048–2049. - PubMed
    1. The relationship between mast cell activation syndrome, postural tachycardia syndrome, and Ehlers-Danlos syndrome. Wang E, Ganti T, Vaou E, Hohler A. Allergy Asthma Proc. 2021;42:243–246. - PubMed
    1. The relationship between hypermobile Ehlers-Danlos Syndrome (hEDS), postural orthostatic tachycardia syndrome (POTS), and mast cell activation syndrome (MCAS) Kohn A, Chang C. Clin Rev Allergy Immunol. 2020;58:273–297. - PubMed

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