Mycophenolate mofetil plus steroids compared to steroids alone in IgA nephropathy: a retrospective study

Francesco Fontana¹, Marco Delsante^{2

3}, Manuela Vicari⁴, Chiara Pala^{2

3}, Gaetano Alfano⁵, Silvia Giovanella⁴, Giulia Ligabue⁴, Marco Leonelli⁵, Lucio Manenti^{2

3}, Giovanni Maria Rossi^{2

3}, Riccardo Magistroni^{5

4}, Enrico Fiaccadori^{2

3}, Gabriele Donati^{5

4}

Affiliations

¹ Nephrology, Dialysis and Kidney Transplant Unit, Azienda Ospedaliero-Universitaria di Modena, Modena, Italy. francesco.fontana@unimore.it.
² Nephrology Unit, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.
³ Medical and Surgical Department, University of Parma, Parma, Italy.
⁴ Surgical Medical and Dental Department of Morphological Sciences, University of Modena and Reggio Emilia, Modena, Italy.
⁵ Nephrology, Dialysis and Kidney Transplant Unit, Azienda Ospedaliero-Universitaria di Modena, Modena, Italy.

Francesco Fontana et al. J Nephrol. 2023 Mar.

. 2023 Mar;36(2):297-300.

doi: 10.1007/s40620-023-01578-z. Epub 2023 Feb 15.

¹ Nephrology, Dialysis and Kidney Transplant Unit, Azienda Ospedaliero-Universitaria di Modena, Modena, Italy. francesco.fontana@unimore.it.
² Nephrology Unit, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.
³ Medical and Surgical Department, University of Parma, Parma, Italy.
⁴ Surgical Medical and Dental Department of Morphological Sciences, University of Modena and Reggio Emilia, Modena, Italy.
⁵ Nephrology, Dialysis and Kidney Transplant Unit, Azienda Ospedaliero-Universitaria di Modena, Modena, Italy.

No abstract available

Keywords: IgA nephropathy; Mycophenolate mofetil; Steroid.

References

1. Rovin BH, Adler SG, Barratt J, KDIGO et al (2021) Clinical practice guideline for the management of glomerular diseases. Kidney Int Suppl 2021:2021. https://doi.org/10.1016/j.kint.2021.05.021 - DOI
1. Manno C, Torres DD, Rossini M, Pesce F, Schena FP (2009) Randomized controlled clinical trial of corticosteroids plus ACE-inhibitors with long-term follow-up in proteinuric IgA nephropathy. Nephrol Dial Transplant 24(12):3694–3701. https://doi.org/10.1093/ndt/gfp356 - DOI - PubMed
1. Pozzi C, Bolasco PG, Fogazzi GB et al (1999) Corticosteroids in IgA nephropathy: a randomised controlled trial. Lancet (London, England) 353(9156):883–887 - DOI - PubMed
1. Lv J, Wong MG, Hladunewich MA et al (2022) Effect of oral methylprednisolone on decline in kidney function or kidney failure in patients with IgA nephropathy: The TESTING Randomized Clinical Trial. JAMA 327(19):1888. https://doi.org/10.1001/JAMA.2022.5368 - DOI - PubMed - PMC
1. Tang SCW, Tang AWC, Wong SSH, Leung JCK, Ho YW, Lai KN (2010) Long-term study of mycophenolate mofetil treatment in IgA nephropathy. Kidney Int 77(6):543–549. https://doi.org/10.1038/ki.2009.499 - DOI - PubMed