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Comment
. 2023 Feb 14;56(2):229-231.
doi: 10.1016/j.immuni.2023.01.019.

Breathing easy: Dopamine quenches the ILC2 flame

Franz Puttur  1 , Clare M Lloyd  2
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Free article
Comment

Breathing easy: Dopamine quenches the ILC2 flame

Franz Puttur et al. Immunity. .
Free article

Abstract

Communication between nerves and group 2 innate lymphoid cells (ILC2s) is thought to regulate allergic airway inflammation, but the molecular mechanisms are unclear. In this issue of Immunity, Cao et al. uncover an essential role for dopamine in inhibiting ILC2 function via metabolic restriction, thereby ameliorating key features of asthma pathogenesis.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

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