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. 1987 Oct;62(2):307-13.

A human cell-surface glycoprotein that carries Cromer-related blood group antigens on erythrocytes and is also expressed on leucocytes and platelets

F A Spring  1 , P A Judson, G L Daniels, S F Parsons, G Mallinson, D J Anstee
Affiliations

A human cell-surface glycoprotein that carries Cromer-related blood group antigens on erythrocytes and is also expressed on leucocytes and platelets

F A Spring et al. Immunology. 1987 Oct.

Abstract

A new human erythrocyte glycoprotein has been identified by immunoblotting with murine monoclonal antibodies under non-reducing conditions. The glycoprotein has a MW of 70,000 and carries Cromer-related blood group antigens. The monoclonal antibodies also react with normal peripheral blood leucocytes and platelets and several haemopoietic cell lines. The glycoprotein has a reduced MW after sialidase treatment. The MW is markedly reduced in Tn erythrocyte membranes and slightly increased in Cad erythrocyte membranes. These results suggest that the glycoprotein has a substantial content of O-glycans. The glycoprotein appears to be absent from, or grossly altered in, the erythrocytes of two individuals with the rare Inab phenotype.

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References

    1. Rev Fr Transfus. 1968 Oct 3;11(3):209-21 - PubMed
    1. J Immunol. 1964 May;92:682-92 - PubMed
    1. J Biol Chem. 1970 Dec 10;245(23):6357-65 - PubMed
    1. Transfusion. 1972 Sep-Oct;12(5):352-3 - PubMed
    1. Br J Haematol. 1974 Oct;28(2):253-60 - PubMed

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