Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2023 Jan 14;15(1):e33770.
doi: 10.7759/cureus.33770. eCollection 2023 Jan.

An Unusual Case of Haemophilus parainfluenzae Endocarditis in a Young Patient With Crohn's Disease

Affiliations
Case Reports

An Unusual Case of Haemophilus parainfluenzae Endocarditis in a Young Patient With Crohn's Disease

Vishrut Shah et al. Cureus. .

Abstract

We present a rare case of infective endocarditis (IE) associated with Haemophilus parainfluenzae in a 40-year-old male patient with a history of Crohn's Disease (CD). A complete workup, including an echocardiogram and blood cultures, revealed mitral valve vegetation colonized by H. parainfluenzae. The patient was started on appropriate antibiotics with follow-up for outpatient surgery. This case discusses the potential for ectopic colonization of heart valves by H. parainfluenzae in patients with CD. The presence of this organism as the offending agent in this patient's case of IE shines a light on the pathogenesis of CD. Although uncommon, CD-associated bacterial seeding should be a differential when assessing young patients with IE.

Keywords: anemia; bacterial translocation; crohn’s disease (cd); haemophilus parainfluenzae; infective endocarditis.

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Transesophageal Echocardiogram Performed Demonstrating a Posterior Mitral Valve Leaflet Vegetation

Similar articles

References

    1. Chu Chu, VH VH. UpToDate. Waltham, MA: UpToDate; [ Jul; 2022 ]. 2022. Native valve endocarditis: Epidemiology, risk factors, and microbiology.
    1. Infective endocarditis: a contemporary update. Rajani R, Klein JL. Clin Med. 2020;20:31–35. - PMC - PubMed
    1. Simberkoff MS. Goldman's Cecil Medicine (Twenty Fourth Edition) Philadelphia: W.B. Saunders; 2012. Haemophilus and Moraxella Infections; pp. 1861–1864.
    1. Infective endocarditis. Cahill TJ, Prendergast BD. Lancet. 2016;387:882–893. - PubMed
    1. Experimental bacterial endocarditis: I. Colonization of a sterile vegetation. Durack DT, Beeson PB. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2072378/ Br J Exp Pathol. 1972;53:44–49. - PMC - PubMed

Publication types

LinkOut - more resources