An Unusual Case of Haemophilus parainfluenzae Endocarditis in a Young Patient With Crohn's Disease
- PMID: 36793806
- PMCID: PMC9924830
- DOI: 10.7759/cureus.33770
An Unusual Case of Haemophilus parainfluenzae Endocarditis in a Young Patient With Crohn's Disease
Abstract
We present a rare case of infective endocarditis (IE) associated with Haemophilus parainfluenzae in a 40-year-old male patient with a history of Crohn's Disease (CD). A complete workup, including an echocardiogram and blood cultures, revealed mitral valve vegetation colonized by H. parainfluenzae. The patient was started on appropriate antibiotics with follow-up for outpatient surgery. This case discusses the potential for ectopic colonization of heart valves by H. parainfluenzae in patients with CD. The presence of this organism as the offending agent in this patient's case of IE shines a light on the pathogenesis of CD. Although uncommon, CD-associated bacterial seeding should be a differential when assessing young patients with IE.
Keywords: anemia; bacterial translocation; crohn’s disease (cd); haemophilus parainfluenzae; infective endocarditis.
Copyright © 2023, Shah et al.
Conflict of interest statement
The authors have declared that no competing interests exist.
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References
-
- Chu Chu, VH VH. UpToDate. Waltham, MA: UpToDate; [ Jul; 2022 ]. 2022. Native valve endocarditis: Epidemiology, risk factors, and microbiology.
-
- Simberkoff MS. Goldman's Cecil Medicine (Twenty Fourth Edition) Philadelphia: W.B. Saunders; 2012. Haemophilus and Moraxella Infections; pp. 1861–1864.
-
- Infective endocarditis. Cahill TJ, Prendergast BD. Lancet. 2016;387:882–893. - PubMed
-
- Experimental bacterial endocarditis: I. Colonization of a sterile vegetation. Durack DT, Beeson PB. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2072378/ Br J Exp Pathol. 1972;53:44–49. - PMC - PubMed
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