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. 2023 Jan 6;8(Pt 1):x221209.
doi: 10.1107/S2414314622012093. eCollection 2023 Jan.

(S)-2-[(S)-2,2,2-Tri-fluoro-1-hy-droxy-eth-yl]-1-tetra-lone

Klemen Motaln  1   2 , Andrej Emanuel Cotman  3 , Matic Lozinšek  1   2
Affiliations

(S)-2-[(S)-2,2,2-Tri-fluoro-1-hy-droxy-eth-yl]-1-tetra-lone

Klemen Motaln et al. IUCrdata. .

Abstract

The crystal structure of the title compound, C12H11F3O2, was elucidated by low-temperature single-crystal X-ray diffraction. The enanti-opure compound crystallizes in the Sohncke space group P21 and features one mol-ecule in the asymmetric unit. The structure displays inter-molecular O-H⋯O hydrogen bonding, which links the mol-ecules into infinite chains propagating parallel to [010]. The absolute configuration was established from anomalous dispersion.

Keywords: O—H⋯O hydrogen bonding; asymmetric catalysis; crystal structure; tetra­lone.

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Figures

Figure 1
Figure 1
Mol­ecular structure of the title compound and the atom-labeling scheme. Displacement ellipsoids are shown at the 50% probability level and hydrogen atoms are depicted as spheres of arbitrary radius.
Figure 2
Figure 2
Inter­molecular O—H⋯O=C hydrogen bonds connect the mol­ecules into infinite zigzag chains running parallel to [010].
Figure 3
Figure 3
Packing diagrams of the title compound viewed along [100] (top), [010] (middle), and [001] (bottom).
See this image and copyright information in PMC

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References

    1. Barcon, A., Brunskill, A. P. J., Lalancette, R. A., Thompson, H. W. & Miller, A. J. (2001). Acta Cryst. C57, 325–328. - PubMed
    1. Brandenburg, K. (2005). DIAMOND. Crystal Impact GbR, Bonn, Germany.
    1. Cooper, R. I., Thompson, A. L. & Watkin, D. J. (2010). J. Appl. Cryst. 43, 1100–1107.
    1. Cotman, A. E. (2021). Chem. Eur. J. 27, 39–53. - PubMed
    1. Cotman, A. E., Cahard, D. & Mohar, B. (2016). Angew. Chem. Int. Ed. 55, 5294–5298. - PubMed

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