doi: 10.1007/BF00286965.
The testis as a secretory organ for H-Y antigen
- PMID: 367945
- DOI: 10.1007/BF00286965
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The testis as a secretory organ for H-Y antigen
Hum Genet.
.
Abstract
After cultivation of dissociated rat testicular tissues, H-Y antigen is detectable in the medium; this is not the case if nongonadal male tissues are incubated. Release of H-Y antigen by testis cells is inhibited by the addition of cycloheximide. All tissues still type H-Y positive after culture. It is assumed that the testis actively secretes H-Y antigen. This assumption is supported by the finding that the amount of H-Y antigen in the epididymal fluid increases with the age of the animals.
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