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Editorial
. 2023 Feb 16;141(7):687-689.
doi: 10.1182/blood.2022019181.

MLL1 is central to macrophage-mediated inflammation

Matthew A Schaller  1
Affiliations
Editorial

MLL1 is central to macrophage-mediated inflammation

Matthew A Schaller. Blood. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflict-of-interest disclosure: The author declares no competing financial interests.

Figures

None
MLL1 is central to macrophage activation. A summary of the work by Sharma et al, depicting increased MLL1 expression in macrophages due to IFNs produced as a result of pulmonary coronavirus infection. MLL1 expression is a key factor in macrophage activation, causing coagulopathy and inflammation and inducing an antiviral response. Professional illustration by Patrick Lane, ScEYEnce Studios.
See this image and copyright information in PMC

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References

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    1. Davis FM, Schaller MA, Dendekker A, et al. Sepsis induces prolonged epigenetic modifications in bone marrow and peripheral macrophages impairing inflammation and wound healing. Arterioscler Thromb Vasc Biol. 2019;39(11):2353–2366. - PMC - PubMed

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