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. 2023 Mar 28;4(1):e220134.
doi: 10.1530/RAF-22-0134. Print 2023 Jan 1.

Impact of taxane-based chemotherapeutics on male reproductive function

Charvi Kanodia  1 , Michael P Rimmer  2 , Kathleen Duffin  3 , Rod T Mitchell  2
Affiliations

Impact of taxane-based chemotherapeutics on male reproductive function

Charvi Kanodia et al. Reprod Fertil. .

Abstract

Men and boys with cancer treated with chemotherapy are known to have reduced fertility following their treatment. This is because some chemotherapy drugs can damage the cells in the testicles that make sperm. This study found there is limited information available on the effect of one group of chemotherapy drugs, called taxanes, on testicular function and fertility. More studies are needed to aid clinicians in advising patients on how this taxane-based chemotherapy may affect their future fertility.

Keywords: chemotherapy; fertility; fertility preservation; paclitaxel; taxanes.

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Conflict of interest statement

The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of this review.

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