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. 1987 Oct;13(3):265-72.
doi: 10.1016/0165-5876(87)90107-8.

Choanal atresia and associated anomalies

J E Leclerc  1 , B Fearon
Affiliations

Choanal atresia and associated anomalies

J E Leclerc et al. Int J Pediatr Otorhinolaryngol. 1987 Oct.

Abstract

The authors have studied 130 cases of choanal malformation. They found 53 bilateral atresias, 51 unilateral atresias and 26 cases of choanal stenosis. Fifty-seven of these cases were associated with other anomalies and 38 had at least two features of the CHARGE association (C, colobomas; H, heart defects; A, atresia choanae; R, retarded growth; G, genito-urinary defects; E, ear defects). The pathogenesis of choanal atresia in regard to the abnormal migration of neuroectodermal cells is discussed.

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