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. 2023 Feb;30(2):129-130.
doi: 10.1038/s41594-023-00924-w.

Structural biology at the scale of proteomes

Nazim Bouatta  1 , Mohammed AlQuraishi  2
Affiliations

Structural biology at the scale of proteomes

Nazim Bouatta et al. Nat Struct Mol Biol. 2023 Feb.

Abstract

AlphaFold2 has already changed structural biology but its true power may lie in how it changes the way we think about cells and organisms. Two studies broadly analyze and assess the performance of AlphaFold2 to outline the extent of its utility and limitations in providing structural models that shed light on biological questions, including mutations, post-translational modifications, and protein-protein complex interactions.

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Conflict of interest statement

Conflict of interest

M.A. is a member of the Scientific Advisory Boards of Cyrus Biotechnology, Deep Forest Sciences, Nabla Bio, Oracle Therapeutics, and FL2021-002, a Foresite Labs company.

References

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