Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 May;58(5):1535-1541.
doi: 10.1002/ppul.26356. Epub 2023 Feb 24.

Outpatient respiratory outcomes in children with BPD on supplemental oxygen

Julianne R McGlynn  1 , Brianna C Aoyama  2 , Amanda Martin  1 , Joseph M Collaco  2 , Sharon A McGrath-Morrow  1
Affiliations

Outpatient respiratory outcomes in children with BPD on supplemental oxygen

Julianne R McGlynn et al. Pediatr Pulmonol. 2023 May.

Abstract

Introduction: Preterm children with bronchopulmonary dysplasia (BPD) frequently require supplemental oxygen in the outpatient setting. In this study, we sought to determine patient characteristics and demographics associated with need for supplemental oxygen at initial hospital discharge, timing to supplemental oxygen liberation, and associations between level of supplemental oxygen and likelihood of respiratory symptoms and acute care usage in the outpatient setting.

Methods: A retrospective analysis of subjects with BPD on supplemental oxygen (O2 ) was performed. Subjects were recruited from outpatient clinics at Johns Hopkins University and the Children's Hospital of Philadelphia between 2008 and 2021. Data were obtained by chart review and caregiver questionnaires.

Results: Children with BPD receiving ≥1 L of O2 were more likely to have severe BPD, pulmonary hypertension, and be older at initial hospital discharge. Children discharged on higher levels of supplemental O2 were slower to wean to room air compared to lower O2 groups (p < 0.001). Additionally, weaning off supplemental O2 in the outpatient setting was delayed in children with gastrostomy tubes and those prescribed inhaled corticosteroids, on public insurance or with lower household incomes. Level of supplemental O2 at discharge did not influence outpatient acute care usage or respiratory symptoms.

Conclusion: BPD severity and level of supplemental oxygen use at discharge did not correlate with subsequent acute care usage or respiratory symptoms in children with BPD. Weaning of O2 however was significantly associated with socioeconomic status and respiratory medication use, contributing to the variability in O2 weaning in the outpatient setting.

Keywords: bronchopulmonary dysplasia; outpatient; socioeconomic status; supplemental oxygen.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Kaplan-Meier plot with time to weaning from home supplemental oxygen by amount of oxygen at initial hospital discharge
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Martin JA, Hamilton BE & Osterman MJK Births in the United States, 2019. NCHS Data Brief, 1–8 (2020). - PubMed
    1. Bell EF et al. Mortality, In-Hospital Morbidity, Care Practices, and 2-Year Outcomes for Extremely Preterm Infants in the US, 2013–2018. Jama 327, 248–263, doi:10.1001/jama.2021.23580 (2022). - DOI - PMC - PubMed
    1. Yeh J, McGrath-Morrow SA & Collaco JM Oxygen weaning after hospital discharge in children with bronchopulmonary dysplasia. Pediatr Pulmonol 51, 1206–1211, doi:10.1002/ppul.23442 (2016). - DOI - PMC - PubMed
    1. Hayes D Jr. et al. Home Oxygen Therapy for Children. An Official American Thoracic Society Clinical Practice Guideline. American journal of respiratory and critical care medicine 199, e5–e23, doi:10.1164/rccm.201812-2276ST (2019). - DOI - PMC - PubMed
    1. Balfour-Lynn IM et al. BTS guidelines for home oxygen in children. Thorax 64 Suppl 2, ii1–26, doi:10.1136/thx.2009.116020 (2009). - DOI - PubMed

Publication types