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Comment
. 2023 Jun;14(6):741-743.
doi: 10.1111/jdi.13994. Epub 2023 Feb 17.

Commentary on glucose reduction in type 2 diabetes (GRADE)

Affiliations
Comment

Commentary on glucose reduction in type 2 diabetes (GRADE)

Yi-Hong Lee et al. J Diabetes Investig. 2023 Jun.
No abstract available

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Comment on

  • Glycemia Reduction in Type 2 Diabetes - Glycemic Outcomes.
    GRADE Study Research Group; Nathan DM, Lachin JM, Balasubramanyam A, Burch HB, Buse JB, Butera NM, Cohen RM, Crandall JP, Kahn SE, Krause-Steinrauf H, Larkin ME, Rasouli N, Tiktin M, Wexler DJ, Younes N. GRADE Study Research Group, et al. N Engl J Med. 2022 Sep 22;387(12):1063-1074. doi: 10.1056/NEJMoa2200433. N Engl J Med. 2022. PMID: 36129996 Free PMC article. Clinical Trial.
  • Glycemia Reduction in Type 2 Diabetes - Microvascular and Cardiovascular Outcomes.
    GRADE Study Research Group; Nathan DM, Lachin JM, Bebu I, Burch HB, Buse JB, Cherrington AL, Fortmann SP, Green JB, Kahn SE, Kirkman MS, Krause-Steinrauf H, Larkin ME, Phillips LS, Pop-Busui R, Steffes M, Tiktin M, Tripputi M, Wexler DJ, Younes N. GRADE Study Research Group, et al. N Engl J Med. 2022 Sep 22;387(12):1075-1088. doi: 10.1056/NEJMoa2200436. N Engl J Med. 2022. PMID: 36129997 Free PMC article. Clinical Trial.

References

    1. Nathan DM, Lachin JM, Balasubramanyam A, et al. Glycemia reduction in type 2 diabetes – glycemic outcomes: a multicenter, parallel‐group, comparative‐effectiveness clinical trial. N Engl J Med 2022; 387: 1063–1074. - PMC - PubMed
    1. Nathan DM, Lachin JM, Bebu I, et al. Glycemia reduction in type 2 diabetes – microvascular and cardiovascular outcomes: a multicenter, parallel‐group, comparative‐effectiveness clinical trial. N Engl J Med 2022; 387: 1075–1088. - PMC - PubMed
    1. Marso SP, Daniels GH, Brown‐Frandsen K, et al. LEADER Steering Committee, LEADER Trial Investigators Liraglutide and cardiovascular outcomes in type 2 diabetes: a multicenter, double‐blind, placebo‐controlled trial. N Engl J Med 2016; 375: 311–322. - PMC - PubMed
    1. Sun F, Chai S, Yu K, et al. Gastrointestinal adverse events of glucagon‐like peptide‐1 receptor agonists in patients with type 2 diabetes: a systematic review and network meta‐analysis. Diabetes Technol Ther 2015; 17: 35–42. - PMC - PubMed
    1. Zang L, Liu Y, Geng J, et al. Efficacy and safety of liraglutide versus sitagliptin, both in combination with metformin, in Chinese patients with type 2 diabetes: a 26‐week, open‐label, randomized, active comparator clinical trial. Diabetes Obes Metab 2016; 18: 803–811. - PMC - PubMed