Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Jun 8;76(11):2014-2017.
doi: 10.1093/cid/ciad087.

Effect of Coronavirus Disease 2019 Lockdowns on Identification of Advanced Human Immunodeficiency Virus Disease in Outpatient Clinics in Uganda

Affiliations

Effect of Coronavirus Disease 2019 Lockdowns on Identification of Advanced Human Immunodeficiency Virus Disease in Outpatient Clinics in Uganda

Elizabeth Nalintya et al. Clin Infect Dis. .

Abstract

Using data from 67 Ugandan human immunodeficiency virus (HIV) clinics (July 2019-January 2022), we report a 40% (1005/1662) reduction in the number of people with HIV presenting to care after August 2021 compared to prepandemic levels, with a greater proportion presenting with advanced HIV disease (20% vs 16% in the pre-coronavirus disease 2019 period).

Keywords: COVID-19; advanced HIV disease; opportunistic infections.

PubMed Disclaimer

Conflict of interest statement

Potential conflicts of interest. The authors: No reported conflicts of interest. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest.

Figures

Figure 1.
Figure 1.
Number of PWH presenting to HIV care by month. Blue bars represent PWH with CD4>200 cells/µL. Orange bars represent PWH with advanced HIV disease (CD4≤200 cells/µL). Covid-19 cases in Uganda plotted in dashed black line. There has been a marked decline in overall number of PWH presenting to care since onset of the Covid-19 pandemic, though the absolute number with advanced HIV disease remains stable.

References

    1. Osler M, Hilderbrand K, Goemaere E, et al. . The continuing burden of advanced HIV disease over 10 years of increasing antiretroviral therapy coverage in South Africa. Clin Infect Dis 2018; 66(Suppl 2):S118–25. - PMC - PubMed
    1. Lamp K, McGovern S, Fong Y, et al. . Proportions of CD4 test results indicating advanced HIV disease remain consistently high at primary health care facilities across four high HIV burden countries. PLoS One 2020; 15:e0226987. - PMC - PubMed
    1. Carmona S, Bor J, Nattey C, et al. . Persistent high burden of advanced HIV disease among patients seeking care in South Africa’s national HIV program: data from a nationwide laboratory cohort. Clin Infect Dis 2018; 66(Suppl 2):S111––7.. - PMC - PubMed
    1. US President’s Emergency Plan for AIDS Relief . Country operational plan guidance for all PEPFAR countries. Washington, DC: US Department of State, 2019.
    1. World Health Organization (WHO) . Guidelines for managing advanced HIV disease and rapid initiation of antiretroviral therapy. Geneva, Switzerland: WHO, 2017:56. - PubMed

Publication types