Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Feb 21;4(2):100936.
doi: 10.1016/j.xcrm.2023.100936. Epub 2023 Jan 23.

COVID-19 vaccines versus pediatric hospitalization

Affiliations

COVID-19 vaccines versus pediatric hospitalization

Jaime S Rosa Duque et al. Cell Rep Med. .

Abstract

Vaccine effectiveness of BNT162b2 and CoronaVac against COVID-19-associated hospitalization and moderate-to-severe disease due to SARS-CoV-2 Omicron BA.2 is studied from the 1.36 million doses administered to 766,601 of 953,400 children aged 3-11 years and adolescents aged 12-18 years in Hong Kong as of April 2022. These vaccines confer substantial protection.

PubMed Disclaimer

Conflict of interest statement

Declaration of interests Y.L.L. chairs the Scientific Committee on Vaccine Preventable Diseases of the HK Government.

Figures

None
Graphical abstract

References

    1. Tso W.W.Y., Kwan M.Y.W., Wang Y.L., Leung L.K., Leung D., Chua G.T., Ip P., Fong D.Y.T., Wong W.H.S., Chan S.H.S., et al. Severity of SARS-CoV-2 Omicron BA. 2 infection in unvaccinated hospitalized children: comparison to influenza and parainfluenza infections. Emerg. Microbes Infect. 2022;11:1742–1750. doi: 10.1080/22221751.2022.2093135. - DOI - PMC - PubMed
    1. Leung D., Rosa Duque J.S., Yip K.M., So H.K., Wong W.H.S., Lau Y.L. Effectiveness of BNT162b2 and CoronaVac in children and adolescents against SARS-CoV-2 infection during Omicron BA.2 wave in Hong Kong. Commun. Med. 2023;3:3. doi: 10.1038/s43856-022-00233-1. - DOI - PMC - PubMed
    1. Rosa Duque J.S., Wang X., Leung D., Cheng S.M.S., Cohen C.A., Mu X., Hachim A., Zhang Y., Chan S.M., Chaothai S., et al. Immunogenicity and reactogenicity of SARS-CoV-2 vaccines BNT162b2 and CoronaVac in healthy adolescents. Nat. Commun. 2022;13:3700. doi: 10.1038/s41467-022-31485-z. - DOI - PMC - PubMed
    1. Price A.M., Olson S.M., Newhams M.M., Halasa N.B., Boom J.A., Sahni L.C., Pannaraj P.S., Irby K., Bline K.E., Maddux A.B., et al. BNT162b2 protection against the Omicron variant in children and adolescents. N. Engl. J. Med. 2022;386:1899–1909. doi: 10.1056/NEJMoa2202826. - DOI - PMC - PubMed
    1. Tan S.H.X., Cook A.R., Heng D., Ong B., Lye D.C., Tan K.B. Effectiveness of BNT162b2 vaccine against omicron in children 5 to 11 years of age. N. Engl. J. Med. 2022;387:525–532. doi: 10.1056/NEJMoa2203209. - DOI - PMC - PubMed

Publication types