Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1987 Dec;169(12):5615-21.
doi: 10.1128/jb.169.12.5615-5621.1987.

Genetic studies of avermectin biosynthesis in Streptomyces avermitilis

H Ikeda  1 , H Kotaki, S Omura
Affiliations

Genetic studies of avermectin biosynthesis in Streptomyces avermitilis

H Ikeda et al. J Bacteriol. 1987 Dec.

Abstract

A genetic recombination study of an industrial strain of Streptomyces avermitilis which produces avermectin is described. A genetic map has been constructed by analysis of haploid recombinants and linkage relationships of 16 marker loci. Fifteen avermectin-nonproducing mutants, produced by mutagenesis, were classified into two phenotypically different groups, of which one produced avermectin aglycon and the other was able to convert avermectin aglycon to avermectins. Two different mutants were found to map closely to each other.

PubMed Disclaimer

References

    1. Bacteriol Rev. 1967 Dec;31(4):373-403 - PubMed
    1. Mutat Res. 1970 Feb;9(2):167-82 - PubMed
    1. Genetics. 1969 Jul;62(3):461-77 - PubMed
    1. J Bacteriol. 1971 Mar;105(3):880-5 - PubMed
    1. J Gen Microbiol. 1971 Oct;68(2):187-97 - PubMed

LinkOut - more resources