Nucleotide sequences of the genes for two distinct cephalosporin acylases from a Pseudomonas strain
- PMID: 3680178
- PMCID: PMC214163
- DOI: 10.1128/jb.169.12.5821-5826.1987
Nucleotide sequences of the genes for two distinct cephalosporin acylases from a Pseudomonas strain
Abstract
Two genes, acyI and acyII, for distinct cephalosporin acylases from Pseudomonas sp. strain SE83 (A. Matsuda, K. Matsuyama, K. Yamamoto, S. Ichikawa, and K.I. Komatsu, J. Bacteriol. 169:5815-5820, 1987) were sequenced. Each sequence contained a single open reading frame for two nonidentical subunits, predicting a common precursor. Some homologies at the amino acid level were found between the acyII-encoded enzyme, but not the acyI-encoded one, and other related acylases.
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