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. 1987 Nov;48(11):442-4.

A preliminary study of desipramine in the treatment of cocaine abuse in methadone maintenance patients

T R Kosten  1 , B Schumann, D Wright, M K Carney, F H Gawin
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  • PMID: 3680185

A preliminary study of desipramine in the treatment of cocaine abuse in methadone maintenance patients

T R Kosten et al. J Clin Psychiatry. 1987 Nov.

Abstract

Intravenous cocaine use is a major problem in methadone maintenance programs. In this pilot study of 16 cocaine-abusing methadone maintenance patients, 8 received desipramine and 8 received no medication other than methadone. During an 8-week open trial the desipramine patients reported significantly less cocaine craving and had less cocaine use than the other patients.

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