Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023 Dec 31;19(1):2176640.
doi: 10.1080/21645515.2023.2176640. Epub 2023 Feb 20.

Barriers and facilitators in uptake of human papillomavirus vaccine across English Canada: A review

Affiliations
Review

Barriers and facilitators in uptake of human papillomavirus vaccine across English Canada: A review

Amal Khan et al. Hum Vaccin Immunother. .

Abstract

Human Papillomavirus (HPV) is a highly contagious sexually transmitted infection that leads to preventable cancers of the mouth, throat, cervix, and genitalia. Despite the wide availability of HPV Vaccine (HPVV) in Canada, its uptake remains suboptimal. This review aims to identify factors (barriers and facilitators) in HPV vaccine uptake across English Canada at three levels (provider, system, and patient). We explored academic and gray literature to examine factors involved in HPVV uptake and synthesized results based on interpretive content analysis. The review identified the following factors of prime significance in the uptake of the HPV vaccine (a) at the provider level, 'acceptability' of the HPV vaccine, and 'appropriateness' of an intervention (b) at the patient level, the 'ability to perceive' and 'knowledge sufficiency' (c) at the system level, 'attitudes' of different players in vaccine programming, planning and delivery. Further research is needed to conduct population health intervention research in this area.

Keywords: HPV immunization; Human Papilloma Virus (HPV); papillomavirus infection; preventable cancer; sexually transmitted infections; viral wart.

PubMed Disclaimer

Conflict of interest statement

No potential conflict of interest was reported by the authors.

Figures

Figure 1.
Figure 1.
PRISMA flow diagram.
Figure 2.
Figure 2.
Analytical framework.

References

    1. Canadian Cancer Society’s Advisory Committee on Cancer Statistics . Special topic: hPV-associated cancers. (Members of the Canadian Cancer Statistics Advisory Committee, ed); 2016.
    1. D’souza G, Agrawal Y, Halpern J, Bodison S, Gillison ML.. Oral sexual behaviors associated with prevalent oral human papillomavirus infection. J Infect Dis. 2009;199(9):1263–27. doi:10.1086/597755. - DOI - PMC - PubMed
    1. Dubé E, Gagnon D, Clément P, Bettinger JA, Comeau JL, Deeks S, Guay M, MacDonald S, MacDonald NE, Mijovic H, et al. Challenges and opportunities of school-based HPV vaccination in Canada. Hum Vaccines Immunother. 2019;15(7–8):1650–55. doi:10.1080/21645515.2018.1564440. - DOI - PMC - PubMed
    1. The Canadian Cancer Society . Statistics Canada and the Public Health Agency of Canada, in collaboration with the provincial and territorial cancer registries. A 2022 special report on cancer prevalence; 2022. http://cancer.ca/Canadian-Cancer-Statistics-2022-EN.
    1. Canadian Institute for Health Information . Wait times for priority procedures in Canada, 2021: focus on the first 6 months of the COVID-19 pandemic. Published online 2021. https://www.cihi.ca/sites/default/files/document/wait-times-chartbook-pr....

Publication types

Substances

LinkOut - more resources