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Comment
. 2023 Feb 16;186(4):685-687.
doi: 10.1016/j.cell.2023.01.010.

The cost of competency?

Yun-Ruei Kao  1 , Britta Will  2
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The cost of competency?

Yun-Ruei Kao et al. Cell. .
Free article

Abstract

Curtailed protein translation ensures stemness and multipotency in embryonic and adult tissue-specific stem cells. In this issue of Cell, a study led by Zhao and colleagues uncovered increased susceptibility of hematopoietic stem cells (HSC) to iron-dependent programmed necrotic cell death (ferroptosis) as a consequence of low protein synthesis.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

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