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. 2023 Feb 21;72(1):93-99.
doi: 10.33073/pjm-2023-001. Print 2023 Mar 1.

Changes in the Protein Profile in Staphylococcal Strains from Patients Infected with the SARS-CoV-2 Virus

Tomasz Jarzembowski  1 , Lidia Piechowicz  1 , Marek Bronk  2 , Anna Pałubicka  3 , Łukasz Naumiuk  2
Affiliations

Changes in the Protein Profile in Staphylococcal Strains from Patients Infected with the SARS-CoV-2 Virus

Tomasz Jarzembowski et al. Pol J Microbiol. .

Abstract

Staphylococcus aureus strains are particularly often isolated from patients with SARS-CoV-2 infection. The aim of the current research was to determine whether the SARS-CoV-2 virus infection affects the protein profile of S. aureus. Bacteria were isolated from the forty swabs collected from the patients in the hospitals of the Pomeranian region. MALDI-TOF MS spectra were obtained using a Microflex LT instrument. Twenty-nine peaks were identified. The peak (2,430) is described here for the first time and was unique for the isolates from patients infected with the SARS-CoV-2 virus. These results support the hypothesis of bacterial adaptation to the conditions caused by viral infection.

Keywords: MALDI-TOF; SARS-CoV-2; Staphylococcus aureus; source of isolation.

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Conflict of interest statement

Conflict of interest: The authors do not report any financial or personal connections with other persons or organizations, which might negatively affect the contents of this publication and/or claim authorship rights to this publication.

Figures

Fig. 1.
Fig. 1.
Classification and Regression Trees of the strains studied by the protein presence and relative amount of particular protein. Red boxes represent the identified categories, while vertical bars are the source of strains.
Fig. 2.
Fig. 2.
ANOVA comparison of relative protein peak intensity in isolates from different groups of patients.
None
See this image and copyright information in PMC

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