Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Jun;130(6):655-658.
doi: 10.1016/j.ophtha.2023.02.013. Epub 2023 Feb 16.

Characteristics and Management of Ocular Involvement in Individuals with Monkeypox Disease

Affiliations

Characteristics and Management of Ocular Involvement in Individuals with Monkeypox Disease

Marta Pazos et al. Ophthalmology. 2023 Jun.
No abstract available

Keywords: Keratitis; Ocular involvement; Steroids; Tecovirimat; mpox.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Eye appearance and follow-up evolution of the 5 patients with more severe ocular manifestations. AD, Patient 1, who demonstrated significant conjunctivitis at presentation (A) and showed geographical corneal ulcers (B) that evolved to severe thinning 8 days later (C). One week after Tecovirimat administration, the corneal lesions started to improve, with healing 1 month after presentation (D). EH, Patient 2, who demonstrated eyelid papules (E) and membranous conjunctivitis with focal conjunctival erosions in the left eye (F) that extended over time and closed after 2 weeks of treatment with povidone–iodine and oxytetracycline plus polymyxin plus hydrocortisone ointment. Twenty days after initially seeking treatment, he demonstrated corneal involvement with semilunar corneal ulceration and Dellen (G) that infiltrated in the ensuing 5 days with stromal corneal edema (H). IK, Patient 3, who showed eyelid papules (I) and membranous and mucopurulent conjunctivitis and conjunctival erosions (J) that were resolved 28 days after presentation (K). LN, Patient 6, who demonstrated severe unilateral eyelid edema (L) and membranous conjunctivitis (M). Three days after presentation, he demonstrated cellulitis with restriction of the medium rectus and was admitted (N). OQ, Patient 9 with peripheral corneal semilunar infiltrates (O, P) that evolved to corneal thinning with stromal edema (Q).

References

    1. World Health Organization https://www.who.int/news-room/fact-sheets/detail/monkeypox Available at:
    1. Jezek Z., Szczeniowski M., Paluku K.M., Mutombo M. Human monkeypox: clinical features of 282 patients. J Infect Dis. 1987;156:293–298. - PubMed
    1. Ogoina D., Iroezindu M., James H.I., et al. Clinical course and outcome of human monkeypox in Nigeria. Clin Infect Dis. 2020;71:e210–e214. - PubMed
    1. Thornhill J.P., Barkati S., Walmsley S., et al. Monkeypox virus infection in humans across 16 countries—April-June 2022. N Engl J Med. 2022;387:679–691. - PubMed
    1. European Center for Disease Prevention and Control https://www.ecdc.europa.eu/en/all-topics-z/monkeypox/factsheet-health-pr... Available at:

Publication types