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Review
. 2023 Mar;37(1):153-173.
doi: 10.1016/j.idc.2022.11.006.

Update in Human Immunodeficiency Virus and Aging

Jason R Faulhaber  1 , Anthony W Baffoe-Bonnie  2 , Krisann K Oursler  3 , Shikha S Vasudeva  3
Affiliations
Review

Update in Human Immunodeficiency Virus and Aging

Jason R Faulhaber et al. Infect Dis Clin North Am. 2023 Mar.

Abstract

Effective and consistent antiretroviral therapy has enabled people with human immunodeficiency virus (HIV) (PWH) to survive longer than previously encountered earlier in the epidemic. Consequently, PWH are subject to the struggles and clinical conditions typically associated with aging. However, the aging process in PWH is not the same as for those who do not have HIV. There is a complex interplay of molecular, microbiologic, and pharmacologic factors that leads to accelerated aging in PWH; this leads to increased risk for certain age-related comorbidities requiring greater vigilance and interventions in routine care.

Keywords: Aging; Antiretroviral therapy; HIV.

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