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Case Reports
. 2023 Mar;33(1):255-260.
doi: 10.1007/s00062-023-01267-1. Epub 2023 Feb 20.

Freiburg Neuropathology Case Conference : A 43-year-old Patient Presenting with a Right-sided, Slowly Progressing, Painless Exophthalmos and Ptosis

B Simon  1   2 , E Wogram  3   2 , A T Camp  4   2 , M Prinz  3   2 , H Urbach  1   2 , D Erny  3   2 , C A Taschner  5   6
Affiliations
Case Reports

Freiburg Neuropathology Case Conference : A 43-year-old Patient Presenting with a Right-sided, Slowly Progressing, Painless Exophthalmos and Ptosis

B Simon et al. Clin Neuroradiol. 2023 Mar.
No abstract available

Keywords: Orbital metastasis; Orbital rhabdomyosarcoma; Orbital schwannoma; Orbital solitary fibrous tumor; Primary orbital lymphoma.

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Conflict of interest statement

B. Simon, E. Wogram, A.T. Camp, M. Prinz, H. Urbach, D. Erny and C.A. Taschner declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
View of the operative site: tumor (A), right eyeball (B), spatulas (C)
Fig. 2
Fig. 2
Axial (a) and coronal (b) T2-weighted images showed an intraorbital, intraconal mass (arrows) located medially of the optic nerve. Cystic components were presented on the lateral tumor margin (arrowheads). Note the right-sided exophthalmos on the axial view (a)
Fig. 3
Fig. 3
On T1-weighted axial images (a) without contrast the lesion (arrow) appeared isointense. On axial (b) and coronal (c) T1-weighted images MRI after administration of Gd the lesion showed homogeneous enhancement of contrast (arrows). The cystic portion of the tumor displayed a contrast-enhancing capsule (c, arrowhead)
Fig. 4
Fig. 4
Hematoxylin-eosin-stained section depicted an isomorphic tumor formation with spindle-shaped cells and a streaming of tumor cells between collagen. Asterisk indicates collagenous stroma. Scale bar: 50 µm
Fig. 5
Fig. 5
Immunohistochemistry: homogeneously positive reaction in the tumor cells for vimentin (a). Tumor cells showed a positive reaction for STAT6 (b). Immunohistochemistry for Ki-67 (Mib1), detected about 1% of all the tumor cells that were proliferating (c) with asterisks indicating two proliferating cells. Immunohistochemistry for CD34 (d) showed a positive reaction in the endothelial cells that constituted the dilated, branched, hyalinized staghorn-like (hemangiopericytoma-like) vasculature. Asterisks indicate a few exemplary vessels. Scale bars: 50 µm
See this image and copyright information in PMC

References

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