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Review
. 2023 Apr:141:93-100.
doi: 10.1016/j.pediatrneurol.2023.01.008. Epub 2023 Jan 20.

Roadmap for the Assessment and Management of Outcomes in Pediatric Stroke

Ryan J Felling  1 , Lori C Jordan  2 , Christine Mrakotsky  3 , Gabrielle deVeber  4 , Rachel K Peterson  5 , Aleksandra Mineyko  6 , Samantha J Feldman  7 , Kevin Shapiro  8 , Warren Lo  9 , Lauren A Beslow  10
Affiliations
Review

Roadmap for the Assessment and Management of Outcomes in Pediatric Stroke

Ryan J Felling et al. Pediatr Neurol. 2023 Apr.

Abstract

Neurological morbidity is common after pediatric stroke, with moderate to severe deficits that can significantly impact education and social function. Care and recovery occur in phases distinguished by the time interval after stroke onset. These phases include the hyperacute and acute periods in which the focus is on cerebral reperfusion and prevention of neurological deterioration, followed by the subacute and chronic phases in which the focus is on secondary stroke prevention and mitigation of disability through rehabilitation, adaptation, and reintegration into the community. In this article, a multidisciplinary group of pediatric stroke experts review the stages of recovery after pediatric stroke with an emphasis on critical assessment time points. Our goal is to encourage increased standardization of outcome assessment to facilitate future clinical trials comparing various treatment and intervention options and advance optimized care for children with stroke.

Keywords: Brain injury; Child; Ischemia; Recovery; Rehabilitation.

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Conflict of interest statement

This work received no direct funding. Ryan Felling reports grant funding from the National Institutes of Health and personal compensation from medicolegal consulting. Lori Jordan reports royalties from Uptodate, Inc and NIH funding for mentoring for this work K24 HL147017. Gabrielle deVeber reports personal compensation from medicolegal consulting. Warren Lo grant funding from the National Institutes of Health. Lauren Beslow reports royalties from Uptodate, Inc.

Figures

Figure 1.
Figure 1.. Phases of Recovery.
The figure provides a framework for post-stroke recovery in children and demonstrates the management focus in each phase. In the subacute and chronic phases, rehabilitation and recovery may continue for a much longer time and may overlap with compensation and reintegration.
See this image and copyright information in PMC

References

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