Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2023 Mar 1;107(3):e78-e79.
doi: 10.1097/TP.0000000000004470. Epub 2023 Feb 21.

RE: Time-dependent Bias Existing in Their Statistical Analysis Must Be Properly Controlled/Avoided Before Drawing Any Conclusions

Affiliations
Comment

RE: Time-dependent Bias Existing in Their Statistical Analysis Must Be Properly Controlled/Avoided Before Drawing Any Conclusions

Jeffrey J Gaynor et al. Transplantation. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors have no conflicts of interest to report.

Comment in

Comment on

References

    1. Lim JH, Kwon S, Jeon Y, et al. The efficacy and safety of SGLT2 inhibitor in diabetic kidney transplant recipients. Transplantation. 2022;106:e404–e412.
    1. Beyersmann J, Gastmeier P, Wolkewitz M, et al. An easy mathematical proof showed that time-dependent bias inevitably leads to biased effect estimation. J Clin Epid. 2008;61:1261–1221.
    1. Suissa S. Immortal time bias in pharmacoepidemiology. Am J Epid. 2008;167:492–499.
    1. Shariff SZ, Cuerden MS, Jain AK, et al. The secret of immortal time bias in epidemiologic studies. J Am Soc Nephrol. 2008;19:841–843.
    1. McGuire DK, Shih WJ, Cosentino F, et al. Association of SGLT2 inhibitors with cardiovascular and kidney outcomes in patients with type 2 diabetes – a meta-analysis. JAMA Cardiol. 2021;6:148–158.

LinkOut - more resources