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Case Reports
. 1987 Oct;50(10):1348-52.
doi: 10.1136/jnnp.50.10.1348.

Biochemical studies in mitochondrial encephalomyopathy

S Goda  1 , S Ishimoto, I Goto, Y Kuroiwa, K Koike, M Koike, M Nakagawa, H Reichmann, S DiMauro
Affiliations
Case Reports

Biochemical studies in mitochondrial encephalomyopathy

S Goda et al. J Neurol Neurosurg Psychiatry. 1987 Oct.

Abstract

The alpha-keto acid dehydrogenase complex and its component enzymes, lactate dehydrogenase, pyruvate carboxylase, cytochrome c oxidase, succinate-cytochrome c reductase, NADH-cytochrome c reductase, and the concentration of cytochromes and enzymes of beta-oxidation in muscle from a patient with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes were studied and no specific defect was found. These results raise the possibility that the mitochondrial changes in the patient may be secondary.

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