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Editorial
. 2023 Apr;151(4):898-900.
doi: 10.1016/j.jaci.2023.02.008. Epub 2023 Feb 21.

Antibody repertoire and autoimmunity

Affiliations
Editorial

Antibody repertoire and autoimmunity

Chrysanthi Skevaki et al. J Allergy Clin Immunol. 2023 Apr.
No abstract available

Keywords: COVID-19; autoimmunity.

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Figures

Fig 1
Fig 1
Schematic of antibody producing pathways. Three main pathways for antibody production are shown. Innate-like B cells produce natural antibodies in an antigen-independent pathway (top). Antigen-dependent pathways include extrafollicular and germinal center pathways, as indicated with associated indicated features tied to primary (prime) and secondary (boosting) responses. Arrows indicate possible B cell differentiation pathways. Different shades of blue indicate variation due to somatic hypermutation and affinity maturation. ASC, Antibody-secreting cells; B, B cells; FDC, follicular dendritic cells; PC, plasma cells; T, T cells.

References

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