doi: 10.1007/BF01066523.
Mean residence time in peripheral tissue
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- PMID: 3681668
- DOI: 10.1007/BF01066523
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Mean residence time in peripheral tissue
J Pharmacokinet Biopharm.
1987 Aug.
Abstract
The published methods for determining the mean residence time for drugs in peripheral tissue are reviewed in terms of assumptions involved, advantages and disadvantages. A method for determining mean transit time in peripheral tissue is proposed; this may be a more useful indicator of the tissue retention properties for drug compounds.
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