Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1987 Aug;15(4):439-50.
doi: 10.1007/BF01066523.

Mean residence time in peripheral tissue

P J McNamara  1 , J C Fleishaker, T L Hayden
Affiliations

Mean residence time in peripheral tissue

P J McNamara et al. J Pharmacokinet Biopharm. 1987 Aug.

Abstract

The published methods for determining the mean residence time for drugs in peripheral tissue are reviewed in terms of assumptions involved, advantages and disadvantages. A method for determining mean transit time in peripheral tissue is proposed; this may be a more useful indicator of the tissue retention properties for drug compounds.

PubMed Disclaimer

References

    1. Antimicrob Agents Chemother. 1985 Sep;28(3):369-74 - PubMed
    1. Drug Metab Dispos. 1985 Jul-Aug;13(4):438-42 - PubMed
    1. J Pharm Belg. 1986 Mar-Apr;41(2):69-74 - PubMed
    1. J Pharmacokinet Biopharm. 1978 Dec;6(6):547-58 - PubMed
    1. J Pharmacokinet Biopharm. 1983 Feb;11(1):93-105 - PubMed