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. 2022 Jan;18(1):1-7.
doi: 10.48305/arya.v18i0.2407.

The effect of home-based cardiac rehabilitation on depression score in patients with ischemic heart disease: A longitudinal clinical trial study

Marjan Jamalian  1 , Alireza Ansari-Moghaddam  2 , Hamidreza Roohafza  3 , Mahdi Mohammadi  2 , Leila Vakili  4 , Mohammad Hadi Abbasi  5 , Safoura Yazdekhasti  1 , Gholamreza Masoudy  5 , Hossein Heidari  6 , Hassan Okati-Aliabad  5 , Masoumeh Sadeghi  7
Affiliations

The effect of home-based cardiac rehabilitation on depression score in patients with ischemic heart disease: A longitudinal clinical trial study

Marjan Jamalian et al. ARYA Atheroscler. 2022 Jan.

Abstract

Background: Depression is common in patients with cardiovascular disease (CVD). Home-based cardiac rehabilitation (HBCR) is a program that alleviates depression. This study aimed to determine and compare HBCR programs and usual care (UC) effects on depression control in patients with ischemic heart disease (IHD).

Methods: This clinical trial study was performed on 259 patients with IHD that were randomly allocated to the HBCR and UC groups for stress management. Data were collected using the "Beck Depression Inventory" (BDI) at baseline and 6 and 12 months. Generalized estimating equation (GEE) models were applied to examine the associations between times of the groups and changes in outcomes over the study times. Data analysis was done in SPSS software at the significance level of 0.05.

Results: A total of 247 participants with a mean age of 55.22 ± 7.40 years participated in this study, and 209 (84.6%) of the study participants were men. Among patients, 128 patients in the UC program and 119 patients in the HBCR program attended at least one of the pre-determined visits (months 6 and 12). The patterns of change of the depression parameter were similar through the course of the study between the two groups (P = 0.04). In the HBCR group, the depression reduced continuously from baseline to 6 months, baseline to 12 months, and 6 to 12 months (P < 0.05). In the UC group, depression was significantly reduced from baseline to 6 months and from baseline to 12 months.

Conclusion: HBCR was effective in continuous reducing of depression scores in long-term follow-up of patients with IHD. These findings suggest that HBCR can alleviate depression in patients who do not participate in hospital-based cardiac rehabilitation (CR).

Keywords: Cardiovascular Rehabilitation; Depression; Exercise Therapy; Myocardial Ischemia.

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Figures

Figure 1
Figure 1
The flow diagram for the randomization process of the study HBCR: Home-based cardiac rehabilitation; UC: Usual care
Figure 2
Figure 2
Change in depression over time in usual care (UC) and home-based cardiac rehabilitation (HBCR) groups
See this image and copyright information in PMC

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References

    1. Roth GA, Mensah GA, Johnson CO, Addolorato G, Ammirati E, Baddour LM, et al. Global burden of cardiovascular diseases and risk factors, 1990-2019: Update From the GBD 2019 Study. J Am Coll Cardiol. 2020;76(25):2982–3021. - PMC - PubMed
    1. Jha MK, Qamar A, Vaduganathan M, Charney DS, Murrough JW. Screening and management of depression in patients with cardiovascular disease: JACC State-of-the-Art Review. J Am Coll Cardiol. 2019;73(14):1827–45. - PMC - PubMed
    1. Whooley MA, de Jonge P, Vittinghoff E, Otte C, Moos R, Carney RM, et al. Depressive symptoms, health behaviors, and risk of cardiovascular events in patients with coronary heart disease. JAMA. 2008;300(20):2379–88. - PMC - PubMed
    1. Myers V, Gerber Y, Benyamini Y, Goldbourt U, Drory Y. Post-myocardial infarction depression: Increased hospital admissions and reduced adoption of secondary prevention measures-a longitudinal study. J Psychosom Res. 2012;72(1):5–10. - PubMed
    1. Versteeg H, Hoogwegt MT, Hansen TB, Pedersen SS, Zwisler AD, Thygesen LC. Depression, not anxiety, is independently associated with 5-year hospitalizations and mortality in patients with ischemic heart disease. J Psychosom Res. 2013;75(6):518–25. - PubMed

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