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. 2023 Feb 6;11(4):780-787.
doi: 10.12998/wjcc.v11.i4.780.

Selective laser trabeculoplasty as adjunctive treatment for open-angle glaucoma vs following incisional glaucoma surgery in Chinese eyes

Jing Zhu  1 , Juan Guo  2
Affiliations

Selective laser trabeculoplasty as adjunctive treatment for open-angle glaucoma vs following incisional glaucoma surgery in Chinese eyes

Jing Zhu et al. World J Clin Cases. .

Abstract

Background: Selective laser trabeculoplasty (SLT) is a relatively safe and effective therapy in lowering intraocular pressures (IOP) for glaucoma.

Aim: To study the long-term effects of SLT on IOP and number of glaucoma medications used in Chinese eyes.

Methods: This is a retrospective study in which 75 eyes of 70 patients with open-angle glaucoma (OAG, n =36) and eyes with prior glaucoma surgery (PGS, n =39) were included. Changes in mean IOP and number of glaucoma medications used evaluated at 1 d, 1 wk, 1 mo, 3 mo, 6 mo, 12 mo, and 36 mo after laser treatment.

Results: All patients (33 male, 37 female) were Chinese. The mean age was 44.34 ± 16.14 years. Mean pre-SLT IOP was 22.75 ± 2.08 mmHg in OAG and 22.52 ± 2.62 mmHg in PGS. Mean IOP was significantly reduced 1 d, 1 wk, 1 mo and 3 mo after laser treatment (P < 0.05, respectively). Whereas, there were no significant differences between baseline and SLT treated groups at the 6th month both in OAG (P = 0.347, P > 0.05) and in PGS (P = 0.309, P > 0.05). Six months after SLT treatment, some patients received retreatment of SLT or were given more topical IOP-lowering medication to control the IOP. By the end of our study, the average IOP decreased to 20.73 ± 1.82 mmHg in OAG and 20.49 ± 1.53 mmHg in PGS groups. The number of glaucoma medications used was significantly reduced until the end of 3 years compared to baseline.

Conclusion: SLT could reduce IOP as adjunctive treatment both in OAG and PGS groups. SLT significantly reduced the number of glaucoma medications used 3-years following treatment in glaucoma patients.

Keywords: Adjunctive treatment; Intraocular pressure; Open-angle glaucoma; Prior glaucoma surgery; Selective laser trabeculoplasty.

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Conflict of interest statement

Conflict-of-interest statement: The authors have no conflict of interest to declare. The authors alone are responsible for the content and writing of the paper.

Figures

Figure 1
Figure 1
A graph revealing the cumulative success rate in selective laser trabeculoplasty using the Kaplan-Meier method. Log Rank (Mantel-Cox), P = 0.591.
See this image and copyright information in PMC

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