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. 2023 Feb 1;13(2):1240-1247.
doi: 10.21037/qims-22-787. Epub 2023 Jan 2.

IgG4-related inflammatory pseudotumor involving the temporal bone disguised as meningioma: a case description and literature analysis

Yuanyuan Chen  1 , Tao Li  2 , Dan Wen  2 , Zhenkai Zhao  3 , Yan Tang  1
Affiliations

IgG4-related inflammatory pseudotumor involving the temporal bone disguised as meningioma: a case description and literature analysis

Yuanyuan Chen et al. Quant Imaging Med Surg. .
No abstract available

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Conflict of interest statement

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://qims.amegroups.com/article/view/10.21037/qims-22-787/coif). The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
CT and MRI findings of the lesion. (A) A CT scan of the head revealed a slightly dense circular shape on the left temporal (arrow), with uniform density and a clear boundary. The bone nearby was destroyed. (B) MRI showed a round, well-defined mass shadow (arrow) on the left temporal part. T1WI of the lesion was isointense, and the apparent diffusion coefficient was hypointense. (C) The T2WI of the lesion remained isointense (arrow). (D) After enhancement, the mass showed uniform enhancement with a clear boundary and a meningeal tail sign (arrow). CT, computed tomography; MRI, magnetic resonance imaging; T1WI, T1-weighted images; T2WI, T2-weighted images.
Figure 2
Figure 2
Histological findings of the lesion. (A) The HE stain showed that the lesion was composed of sclerosing fibrosis associated with lymphoplasmacytic infiltration forming lymph follicles (HE stain, ×50). (B) Obliterative phlebitis (HE stain, ×100). (C) Plasma cells invading the tissues (HE stain, ×400). (D) Immunohistochemical staining revealed fusiform cells negative for EMA (immunohistochemistry, ×100). (E) Numerous plasma cells were positive for CD138 (immunohistochemistry, ×400). (F) Over 60 IgG4-positive cells per high-powered field (immunohistochemistry, ×400). HE, hematoxylin and eosin; EMA, epithelial membrane antigen; IgG4, immunoglobulin G4.
Figure 3
Figure 3
MRI images after 1 and a half years after surgery. The T2WI, FLAIR, and T1WI of the lesion all showed no tumor recurrence at the original tumor lesion (arrow). MRI, magnetic resonance imaging; T1WI, T1-weighted images; T2WI, T2-weighted images; FLAIR, fluid-attenuated inversion recovery.
Figure 4
Figure 4
The timeline of the patient’s medical history, diagnosis, treatment, and follow-up in this case. CT, computed tomography; MRI, magnetic resonance imaging.
See this image and copyright information in PMC

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References

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