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. 2023 Feb;28(8):2300107.
doi: 10.2807/1560-7917.ES.2023.28.8.2300107.

Influenza A(H5N1) detection in two asymptomatic poultry farm workers in Spain, September to October 2022: suspected environmental contamination

Esteban Aznar  1 , Inmaculada Casas  2 , Alejandro González Praetorius  3 , María José Ruano Ramos  4 , Francisco Pozo  2 , María José Sierra Moros  1   5 , María Victoria García Rivera  6 , Azucena Sánchez Sánchez  4 , Elena García Villacieros  7 , Gabriela Saravia  1 , María Iglesias-Caballero  2 , Elena Román Marcos  6 , Lucía García San Miguel  1
Affiliations

Influenza A(H5N1) detection in two asymptomatic poultry farm workers in Spain, September to October 2022: suspected environmental contamination

Esteban Aznar et al. Euro Surveill. 2023 Feb.

Abstract

In autumn 2022, the Spanish Influenza National Reference Laboratory (NRL) confirmed the detection of influenza A(H5N1) in samples from two asymptomatic workers linked to an outbreak in a poultry farm in Spain. Nasopharyngeal swabs were taken according to a national screening protocol for exposed workers. Absence of symptoms, low viral load and negative serology in both workers suggested environmental contamination. These findings motivated an update of the early detection strategy specifying timing and sampling conditions in asymptomatic exposed persons.

Keywords: HPAI A(H5N1); Spain; asymptomatic; highly pathogenic avian influenza; human; outbreak.

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Conflict of interest statement

Conflict of interest: None declared.

Figures

Figure 1
Figure 1
Highly pathogenic avian influenza A(H5N1) outbreaks in birds and mammals, Spain, week 1 2022−week 4 2023 (n = 193)
Figure 2
Figure 2
Geographical location of highly pathogenic avian influenza A(H5N1) animal outbreaks (n = 193) and human detections (n = 2) by municipality, Spain, week 1 2022−week 4 2023
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