DCIS Update: Escalation or De-escalation? Boost, Fractionation, and Omission of Radiation

Affiliations

¹ Department of Radiation Oncology, Warren Alpert School of Medicine, Brown University, Providence, Rhode Island. Electronic address: jhepel@lifespan.org.
² Department of Radiation Oncology, Institut Curie, Paris, France.

Editorial

Jaroslaw T Hepel et al. Int J Radiat Oncol Biol Phys. 2023.

. 2023 Mar 15;115(4):813-816.

doi: 10.1016/j.ijrobp.2022.11.010.

¹ Department of Radiation Oncology, Warren Alpert School of Medicine, Brown University, Providence, Rhode Island. Electronic address: jhepel@lifespan.org.
² Department of Radiation Oncology, Institut Curie, Paris, France.

No abstract available

Comment on

Randomized Phase III Trial Evaluating Radiation Following Surgical Excision for Good-Risk Ductal Carcinoma In Situ: Long-Term Report From NRG Oncology/RTOG 9804.
McCormick B, Winter KA, Woodward W, Kuerer HM, Sneige N, Rakovitch E, Smith BL, Germain I, Hartford AC, O'Rourke MA, Walker EM, Strom EA, Hopkins JO, Pierce LJ, Pu AT, Sumida KNM, Vesprini D, Moughan J, White JR. McCormick B, et al. J Clin Oncol. 2021 Nov 10;39(32):3574-3582. doi: 10.1200/JCO.21.01083. Epub 2021 Aug 18. J Clin Oncol. 2021. PMID: 34406870 Free PMC article. Clinical Trial.
Radiation doses and fractionation schedules in non-low-risk ductal carcinoma in situ in the breast (BIG 3-07/TROG 07.01): a randomised, factorial, multicentre, open-label, phase 3 study.
Chua BH, Link EK, Kunkler IH, Whelan TJ, Westenberg AH, Gruber G, Bryant G, Ahern V, Purohit K, Graham PH, Akra M, McArdle O, O'Brien P, Harvey JA, Kirkove C, Maduro JH, Campbell ID, Delaney GP, Martin JD, Vu TTT, Muanza TM, Neal A, Olivotto IA; BIG 3–07/TROG 07.01 trial investigators. Chua BH, et al. Lancet. 2022 Aug 6;400(10350):431-440. doi: 10.1016/S0140-6736(22)01246-6. Lancet. 2022. PMID: 35934006 Clinical Trial.