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. 2023 Jul:52:10-15.
doi: 10.1016/j.carrev.2023.02.014. Epub 2023 Feb 20.

Cardiovascular Complications in Patients Hospitalized for COVID-19: A Cohort Study in Havana, Cuba

Luis Mariano de la Torre Fonseca  1 , Robert Alarcón Cedeño  2 , Víctor Alfonso Jiménez Díaz  3 , Fabiola Isabel Loor Cedeño  4 , Pablo Juan-Salvadores  5
Affiliations

Cardiovascular Complications in Patients Hospitalized for COVID-19: A Cohort Study in Havana, Cuba

Luis Mariano de la Torre Fonseca et al. Cardiovasc Revasc Med. 2023 Jul.

Abstract

Introduction and objective: At least one in ten patients infected with COVID develop cardiovascular complications during hospitalization, increasing the number of deaths from this cause. However, the determinants of risk are not clearly elucidated. This study aims to determine whether there is a relationship between in-hospital cardiac complications and cardiovascular history and hospital evolution.

Methods: Prospective cohort study of 373 patients with a positive diagnosis of SARS-CoV-2 admitted to an Intensive Care Unit between March and October 2021.

Results: Median age was 69 (IQR: 57-77), 29.2 % of patients presented cardiovascular complications: 21.2 % electrical, 5.9 % acute coronary syndrome and 1.9 % pulmonary thromboembolism. Age RR: 1.02 (95 % CI: 1.00-1.04; p = 0.020) and history of ischemic heart disease RR: 2.23 (95 % CI: 1.27-3.92; p = 0.005) were identified as independent predictors of in-hospital cardiac complications.

Conclusions: Age and history of ischemic heart disease were identified as independent predictor variables of cardiovascular complications in patients admitted with severe COVID-19 involvement; being significantly associated with lower survival.

Keywords: Acute coronary syndrome; COVID-19; Cardiac arrhythmias; Cardiovascular complication; Mortality.

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Conflict of interest statement

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Flowchart of individuals in the study according to the inclusion and exclusion criteria.
Fig. 2
Fig. 2
Distribution of in-hospital cardiovascular complications. AF: Atrial fibrillation, AVB: atrioventricular block, VT: Ventricular tachycardia, SVT: supraventricular tachycardia, STEMI: ST elevation with myocardial infarction, NSTACS: Non-ST elevation acute coronary syndrome, EP: Pulmonary embolism.
Fig. 3
Fig. 3
Multivariate analysis of independent predictors of in-hospital cardiovascular complications.
Fig. 4
Fig. 4
Survival free of in-hospital cardiovascular complications.
See this image and copyright information in PMC

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