Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Jul:52:10-15.
doi: 10.1016/j.carrev.2023.02.014. Epub 2023 Feb 20.

Cardiovascular Complications in Patients Hospitalized for COVID-19: A Cohort Study in Havana, Cuba

Luis Mariano de la Torre Fonseca  1 , Robert Alarcón Cedeño  2 , Víctor Alfonso Jiménez Díaz  3 , Fabiola Isabel Loor Cedeño  4 , Pablo Juan-Salvadores  5
Affiliations

Cardiovascular Complications in Patients Hospitalized for COVID-19: A Cohort Study in Havana, Cuba

Luis Mariano de la Torre Fonseca et al. Cardiovasc Revasc Med. 2023 Jul.

Abstract

Introduction and objective: At least one in ten patients infected with COVID develop cardiovascular complications during hospitalization, increasing the number of deaths from this cause. However, the determinants of risk are not clearly elucidated. This study aims to determine whether there is a relationship between in-hospital cardiac complications and cardiovascular history and hospital evolution.

Methods: Prospective cohort study of 373 patients with a positive diagnosis of SARS-CoV-2 admitted to an Intensive Care Unit between March and October 2021.

Results: Median age was 69 (IQR: 57-77), 29.2 % of patients presented cardiovascular complications: 21.2 % electrical, 5.9 % acute coronary syndrome and 1.9 % pulmonary thromboembolism. Age RR: 1.02 (95 % CI: 1.00-1.04; p = 0.020) and history of ischemic heart disease RR: 2.23 (95 % CI: 1.27-3.92; p = 0.005) were identified as independent predictors of in-hospital cardiac complications.

Conclusions: Age and history of ischemic heart disease were identified as independent predictor variables of cardiovascular complications in patients admitted with severe COVID-19 involvement; being significantly associated with lower survival.

Keywords: Acute coronary syndrome; COVID-19; Cardiac arrhythmias; Cardiovascular complication; Mortality.

PubMed Disclaimer

Conflict of interest statement

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Flowchart of individuals in the study according to the inclusion and exclusion criteria.
Fig. 2
Fig. 2
Distribution of in-hospital cardiovascular complications. AF: Atrial fibrillation, AVB: atrioventricular block, VT: Ventricular tachycardia, SVT: supraventricular tachycardia, STEMI: ST elevation with myocardial infarction, NSTACS: Non-ST elevation acute coronary syndrome, EP: Pulmonary embolism.
Fig. 3
Fig. 3
Multivariate analysis of independent predictors of in-hospital cardiovascular complications.
Fig. 4
Fig. 4
Survival free of in-hospital cardiovascular complications.
See this image and copyright information in PMC

References

    1. Zhou W., Song L., Wang X., Xu Z., Wang S., Wang J., et al. Cardiac injury prediction and lymphocyte immunity and inflammation analysis in hospitalized patients with coronavirus disease 2019 (COVID-19) Int J Cardiol. 2021 Mar 1;326:237–242. doi: 10.1016/j.ijcard.2020.10.049. Available in. Epub 2020 Oct 22. PMID: 33098952; PMCID: PMC7577874. - DOI - PMC - PubMed
    1. Linschoten M., Peters S., van Smeden M., Jewbali L.S., Schaap J., Siebelink H.M., et al. CAPACITY-COVID collaborative consortium. Cardiac complications in patients hospitalised with COVID-19. Eur Heart J Acute Cardiovasc Care. 2020 Dec;9(8):817–823. doi: 10.1177/2048872620974605. Available in. - DOI - PMC - PubMed
    1. Szekely Y., Lichter Y., Taieb P., Banai A., Hochstadt A., Merdler I., et al. Spectrum of cardiac manifestations in COVID-19. A systematic echocardiographic study. Circulación. 2020 28 de julio;142(4):342–353. Epub 2020 29 de mayo. PMID: 32469253; IDPM: PMC7382541. - PMC - PubMed
    1. Kwenandar F., Japar K.V., Damay V., Hariyanto T.I., Tanaka M., Lugito N.P.H., et al. Coronavirus disease 2019 and cardiovascular system: a narrative review. Int J Cardiol Heart Vasc. 2020 <comment>Jun 3</comment>;29 doi: 10.1016/j.ijcha.2020.100557. Available in. - DOI - PMC - PubMed
    1. de la Torre Fonseca L.M. Lesión miocárdica en el paciente con COVID-19. CorSalud. 2020;12(2):171–183. [Internet] Available in: http://www.revcorsalud.sld.cu/index.php/cors/article/view/623/1205.