Primary central nervous system lymphoma: a practical guide for neurologists

Abstract

Primary central nervous system lymphoma is rare, comprising 4% of intracranial neoplasms. Although haematologists or oncologists subsequently manage the condition, it is often neurologists who first make, or at least suspect, the diagnosis. This article reviews the disease, its clinical and radiological features and details the work-up needed to achieve a diagnosis (namely histological or cytological confirmation) and to prepare the patient for treatment. We note the importance of brain biopsy, the role of corticosteroids and the varied treatment options.

Keywords: CLINICAL NEUROLOGY; HAEMATOLOGY; LYMPHOMA; NEUROONCOLOGY; STEROIDS.