Cell therapy for heart failure: lessons learned from SCIENCE
- PMID: 36823785
- DOI: 10.1002/ejhf.2807
Cell therapy for heart failure: lessons learned from SCIENCE
Comment on
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Effect of allogeneic adipose tissue-derived mesenchymal stromal cell treatment in chronic ischaemic heart failure with reduced ejection fraction - the SCIENCE trial.Eur J Heart Fail. 2023 Apr;25(4):576-587. doi: 10.1002/ejhf.2772. Epub 2023 Jan 31. Eur J Heart Fail. 2023. PMID: 36644821 Clinical Trial.
References
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- Savarese G, Becher PM, Lund LH, Seferovic P, Rosano GMC, Coats AJS. Global burden of heart failure: a comprehensive and updated review of epidemiology. Cardiovasc Res. 2023;118:3272-87.
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- Virani SS, Alonso A, Aparicio HJ, Benjamin EJ, Bittencourt MS, Callaway CW, et al. Heart disease and stroke statistics - 2021 update: a report from the American Heart Association. Circulation. 2021;143:e254-743.
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- Borow KM, Yaroshinsky A, Greenberg B, Perin EC. Phase 3 DREAM-HF trial of mesenchymal precursor cells in chronic heart failure: a review of biological plausibility and implementation of flexible clinical trial design. Circ Res. 2019;125:265-81.
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- Braunwald E. Cardiac cell therapy: a call for action. Eur Heart J. 2022;43:2352-3.
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- Fernández-Avilés F, Sanz-Ruiz R, Climent AM, Badimon L, Bolli R, Charron D, et al. Global position paper on cardiovascular regenerative medicine. Eur Heart J. 2017;38:2532-46.
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