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. 2024 Jan;20(1):1-10.
doi: 10.1089/chi.2022.0151. Epub 2023 Feb 24.

Patient-Reported Outcomes to Describe Global Health and Family Relationships in Pediatric Weight Management

Erinn T Rhodes  1 , Thao-Ly T Phan  2 , Elizabeth R Earley  3 , Ihuoma Eneli  4 , Matthew A Haemer  5 , Nikki C Highfield  6 , Saba Khan  7 , Grace Kim  8 , Shelley Kirk  9   10 , Elizabeth Monti Sullivan  6 , Janis M Stoll  11 , Lloyd N Werk  12 , Karen Askov Zeribi  13 , Christopher B Forrest  14 , Carole Lannon  13 ; PEDSnet Healthy Weight Network
Collaborators, Affiliations

Patient-Reported Outcomes to Describe Global Health and Family Relationships in Pediatric Weight Management

Erinn T Rhodes et al. Child Obes. 2024 Jan.

Abstract

Background: Patient-reported outcomes (PROs) can assess chronic health. The study aims were to pilot a survey through the PEDSnet Healthy Weight Network (HWN), collecting PROs in tertiary care pediatric weight management programs (PWMP) in the United States, and demonstrate that a 50% enrollment rate was feasible; describe PROs in this population; and explore the relationship between child/family characteristics and PROs. Methods: Participants included 12- to 18-year-old patients and parents of 5- to 18-year-olds receiving care at PWMP in eight HWN sites. Patient-Reported Outcomes Measurement Information System (PROMIS®) measures assessed global health (GH), fatigue, stress, and family relationships (FR). T-score cut points defined poor GH or FR or severe fatigue or stress. Generalized estimating equations explored relationships between patient/family characteristics and PROMIS measures. Results: Overall, 63% of eligible parents and 52% of eligible children enrolled. Seven sites achieved the goal enrollment for parents and four for children. Participants included 1447 children. By self-report, 44.6% reported poor GH, 8.6% poor FR, 9.3% severe fatigue, and 7.6% severe stress. Multiple-parent household was associated with lower odds of poor GH by parent proxy report [adjusted odds ratio (aOR) 0.69, 95% confidence interval (CI) 0.55-0.88] and poor FR by self-report (aOR 0.36, 95% CI 0.17-0.74). Parents were significantly more likely to report that the child had poor GH and poor FR when a child had multiple households. Conclusions: PROs were feasibly assessed across the HWN, although implementation varied by site. Nearly half of the children seeking care in PWMP reported poor GH, and family context may play a role. Future work may build on this pilot to show how PROs can inform clinical care in PWMP.

Keywords: child; family relationships; health-related quality of life; obesity; patient-reported outcome measures.

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Conflict of interest statement

E.T.R. was previously the Site Principal Investigator for clinical trials sponsored by Merck and Astra Zeneca. E.R.E. is a current employee of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc., Rahway, NJ, USA. E.M.S. is a current employee of Janssen of Johnson and Johnson. All other authors have no competing financial interests.

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