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Review
. 2023 Feb 17;12(2):514.
doi: 10.3390/antiox12020514.

Coenzyme Q10 and Endocrine Disorders: An Overview

David Mantle  1 , Iain Parry Hargreaves  2
Affiliations
Review

Coenzyme Q10 and Endocrine Disorders: An Overview

David Mantle et al. Antioxidants (Basel). .

Abstract

Mitochondrial dysfunction and oxidative stress have been implicated in the pathogenesis of a number of endocrine disorders; this, in turn, suggests a potential role for the vitamin-like substance coenzyme Q10 (CoQ10) in the pathogenesis and treatment of these disorders, on the basis of its key roles in mitochondrial function, and as an antioxidant. In this article we have therefore reviewed the role of CoQ10 deficiency and supplementation in disorders of the thyroid, pancreas, gonads, pituitary and adrenals, with a particular focus on hyperthyroidism, type II diabetes, male infertility and polycystic ovary syndrome.

Keywords: coenzyme Q10; diabetes; hyperthyroidism; male infertility; polycystic ovary syndrome.

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Conflict of interest statement

Mantle is medical advisor to Pharma Nord (UK) Ltd. Pharma Nord Ltd. had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.

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