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Review
. 2023 Jan 17;12(2):188.
doi: 10.3390/antibiotics12020188.

Topical Antibiotic Treatment in Dermatology

Affiliations
Review

Topical Antibiotic Treatment in Dermatology

Matthew Dallo et al. Antibiotics (Basel). .

Abstract

Many indications in dermatology can be effectively managed with topical antibiotics, including acne vulgaris, wound infections, secondarily infected dermatitis, and impetigo. Dermatologists must be familiar with the wide spectrum of topical antibiotics available, including indications, mechanisms of action, adverse events, and spectra of activity. Dermatologists must also keep antibiotic resistance in mind when utilizing these medications. Due to the widespread use of topical antibiotics and their importance in dermatology, a literature review was performed using a systematic search of PubMed and Google Scholar with the terms topical antibiotics, skin infections, dermatology, antimicrobials, and inflammatory dermatoses to identify English-language articles published between 1965-2022 from any country. Relevant publications were manually reviewed for additional content. The following literature review will summarize the common topical antibiotics used in dermatology.

Keywords: antimicrobials; dermatology; inflammatory dermatoses; skin infections; topical antibiotics.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Timeline of discovery and approval of topical antibiotics for impetigo [55,56,57].

References

    1. Stevens D.L., Bisno A.L., Chambers H.F., Dellinger E.P., Goldstein E.J., Gorbach S.L., Hirschmann J.V., Kaplan S.L., Montoya J.G., Wade J.C. Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the Infectious Diseases Society of America. Clin. Infect. Dis. 2014;59:e10–e52. doi: 10.1093/cid/ciu296. - DOI - PubMed
    1. Gelmetti C. Local antibiotics in dermatology. Dermatol. Ther. 2008;21:187–195. doi: 10.1111/j.1529-8019.2008.00190.x. - DOI - PubMed
    1. La Torre F., Nicolai A.P. Amikacin gel administration in the treatment of peristomal dermatitis. Drugs Exp. Clin. Res. 1998;24:153–157. - PubMed
    1. Schulte B.C., Wu W., Rosen T. Azelaic Acid: Evidence-based Update on Mechanism of Action and Clinical Application. J. Drugs Dermatol. 2015;14:964–968. - PubMed
    1. Nazzaro-Porro M., Passi S., Picardo M., Breathnach A.S., Zina G. L’acido azelaico nella terapia dell’acne [Azelaic acid in the treatment of acne] G. Ital. Dermatol. Venereol. 1989;124:175–184. - PubMed

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