Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1987 Oct;5(4):353-7.
doi: 10.1002/mrm.1910050406.

Measurement of lactate accumulation by in vivo proton NMR spectroscopy during global cerebral ischemia in rats

T L Richards  1 , M A Keniry, P R Weinstein, B M Pereira, B T Andrews, E J Murphy, T L James
Affiliations

Measurement of lactate accumulation by in vivo proton NMR spectroscopy during global cerebral ischemia in rats

T L Richards et al. Magn Reson Med. 1987 Oct.

Abstract

In vivo 1H NMR spectral editing techniques were used to monitor cerebral lactate production during remotely controlled temporary forebrain ischemia in rats. The lactate/N-acetylaspartate (NAA) ratio correlated with survival after ischemia and subsequent reperfusion. The lactate/NAA ratio that predicted death after ischemia in rats was estimated to be approximately 1.3.

PubMed Disclaimer

LinkOut - more resources