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. 2023 Feb 17;20(4):3537.
doi: 10.3390/ijerph20043537.

Oral Health-Related Quality of Life throughout Treatment with Clear Aligners in Comparison to Conventional Metal Fixed Orthodontic Appliances: A Systematic Review

Eleftherios G Kaklamanos  1   2   3 , Miltiadis A Makrygiannakis  4 , Athanasios E Athanasiou  2   3
Affiliations

Oral Health-Related Quality of Life throughout Treatment with Clear Aligners in Comparison to Conventional Metal Fixed Orthodontic Appliances: A Systematic Review

Eleftherios G Kaklamanos et al. Int J Environ Res Public Health. .

Abstract

Background: Orthodontic clear aligners constitute an alternative and increasingly used orthodontic treatment modality, offering enhanced esthetics with potential consequences regarding patients' oral health-related quality of life (OHRQoL).

Objective: Summarize and systematically evaluate existing evidence on the OHRQoL of patients treated with orthodontic clear aligners compared to treatment with conventional metal, fixed appliances.

Search methods: We searched without limitations six databases and searched manually the reference lists of relevant studies up to the end of October 2022.

Selection criteria: We looked for data from prospective studies that compared OHRQoL, using instruments that had undergone full psychometric validation, between orthodontic patients with clear aligners and labial, fixed, metal orthodontic appliances.

Data collection and analysis: We extracted the data from the located studies, and we assessed the risk of bias with the Cochrane Collaboration suggested tools. The quality of available evidence was based on the GRADE approach.

Results: Three studies were identified. OHRQoL was impacted less by clear aligners compared to treatment with conventional labially placed, fixed, metal appliances. The exploratory meta-regression, with the time point of assessment as predictor, did not reveal any statistically significant effect. The quality of the available evidence ranged from very low to low.

Conclusions: According to the exploratory synthesis of the limited available dataset, treatment with clear aligners could be associated with better OHRQoL ratings compared to treatment with conventional labially placed, metal, fixed appliances. However, the quality of the presented evidence renders further high-quality studies warranted to be able to reach safer conclusions.

Keywords: OHRQoL; clear aligners; orthodontics; quality of life; systematic review.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Flowchart of records.
Figure 2
Figure 2
Risk of bias assessment [Randomized Controlled Trials] [29].
Figure 3
Figure 3
Risk of bias assessment [Controlled Clinical Trials] [33,34].
Figure 4
Figure 4
Forest Plot of the oral health-related quality of life (OHRQoL) ratings in patients treated with orthodontic aligners compared to those treated with conventional labial brackets [29,33,34].
See this image and copyright information in PMC

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