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. 2023 Feb 7;12(4):1330.
doi: 10.3390/jcm12041330.

Dependence of the Atrioventricular Conduction Time on the Conduction through the Atrioventricular Node and His-Purkinje System

Bartosz Żuchowski  1 , Krzysztof Błaszyk  2 , Jarosław Piskorski  3 , Andrzej Wykrętowicz  1 , Przemysław Guzik  1
Affiliations

Dependence of the Atrioventricular Conduction Time on the Conduction through the Atrioventricular Node and His-Purkinje System

Bartosz Żuchowski et al. J Clin Med. .

Abstract

The electrical depolarization of the heart passes through various structures of the cardiac conduction system, which modify its conduction to different extents. In this study, we investigated the relationship between the atrioventricular conduction time (AV interval) and its contributors, the atrioventricular node (AVN) and the His-Purkinje system (HPS), as represented by the AH and HV intervals, respectively. We also compared sex differences in these intervals and their relations. Resting intracardiac tracings lasting 5 min were obtained from 64 patients (33 women) during an invasive electrophysiological study. The aforementioned intervals were measured for all consecutive beats. The mean AH interval was 85.9 ms, HV 43.7 ms, and AV 129.6 ms. Men had longer AH (80.0 vs. 65.9 ms), HV (38.4 vs. 35.3 ms), and AV intervals (124.7 vs. 108.5 ms) than women. The AV intervals were linearly correlated with AH intervals in all patients (r2 = 0.65). No significant correlation was found between AV and HV intervals in all patients (r2 = 0.05). There were no sex differences in these associations. Our results suggest that the atrioventricular conduction time depends mainly on the conduction through the AVN and less on the HPS. These relations are similar in both sexes, although men had longer conduction times through the AVN, HPS, and total atrioventricular conduction time.

Keywords: His bundle; His–Purkinje system; atrioventricular conduction; atrioventricular node; electrophysiological study.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Example of signal labeling and interval measurement. HRA—high right atrium electrogram, HBE—His bundle electrogram, I, II, aVF, V1, and V6—surface ECG tracing. A: atrial signal, H: His signal, V: ventricular signal, AH: atrium-to-His interval, HV: His-to-ventricles interval (as explained in the text).
Figure 2
Figure 2
Dependency of AV intervals on AH and HV intervals. AH, HV, and AV—explained in the text.
See this image and copyright information in PMC

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