Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2023 Feb 8;12(4):1368.
doi: 10.3390/jcm12041368.

Mild and Moderate Hemophilia A: Neglected Conditions, Still with Unmet Needs

Giancarlo Castaman  1 , Flora Peyvandi  2 , Raimondo De Cristofaro  3 , Berardino Pollio  4 , Dario M N Di Minno  5
Affiliations
Editorial

Mild and Moderate Hemophilia A: Neglected Conditions, Still with Unmet Needs

Giancarlo Castaman et al. J Clin Med. .

Abstract

Hemophilia A (HA) is an inherited X-linked bleeding disorder, caused by the deficiency of coagulation factor VIII (FVIII), with variable clinical phenotypes [...].

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. White G.C., 2nd, Rosendaal F., Aledort L.M., Lusher J.M., Rothschild C., Ingerslev J., Factor VIII and Factor IX Subcommittee Definitions in hemophilia. Recommendation of the scientific subcommittee on factor VIII and factor IX of the scientific and standardization committee of the International Society on Thrombosis and Haemostasis. Thromb. Haemost. 2001;85:560. - PubMed
    1. Bolton-Maggs P.H., Pasi K.J. Haemophilias A and B. Lancet. 2003;361:1801–1809. doi: 10.1016/S0140-6736(03)13405-8. - DOI - PubMed
    1. Mancuso M.E., Bidlingmaier C., Mahlangu J.N., Carcao M., Tosetto A., Subcommittee on Factor VIII’ Factor IX and Rare Coagulation Disorders The predictive value of factor VIII/factor IX levels to define the severity of hemophilia: Communication from the SSC of ISTH. J. Thromb. Haemost. 2018;16:2106–2110. doi: 10.1111/jth.14257. - DOI - PubMed
    1. Den Uijl IE M., Fischer K., Van Der Bom J.G., Grobbee D.E., Rosendaal F.R., Plug I. Clinical outcome of moderate haemophilia compared with severe and mild haemophilia. Haemophilia. 2009;15:83–90. doi: 10.1111/j.1365-2516.2008.01837.x. - DOI - PubMed
    1. Di Minno M.N.D., Ambrosino P., Franchini M., Coppola A., Di Minno G. Arthropathy in Patients with Moderate Hemophilia A: A Systematic Review of the Literature. Semin. Thromb. Hemost. 2013;39:723–731. - PubMed

Publication types