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Review
. 2023 Feb 16;28(4):1862.
doi: 10.3390/molecules28041862.

Spondias sp: Shedding Light on Its Vast Pharmaceutical Potential

Érica Mendes Dos Santos  1 , Janaína Artem Ataide  1 , Julia Cedran Coco  1 , Ana Laura Masquetti Fava  2 , Luiza Aparecida Luna Silvério  1 , Ana Claudia Sueiro  1 , Jéssica Ribeiro Alves Silva  1 , André Moreni Lopes  1 , Ana Cláudia Paiva-Santos  3   4 , Priscila Gava Mazzola  1
Affiliations
Review

Spondias sp: Shedding Light on Its Vast Pharmaceutical Potential

Érica Mendes Dos Santos et al. Molecules. .

Abstract

Many plants are used by the population through popular knowledge passed from generation to generation for the treatment of various diseases. However, there is not always any scientific content supporting these uses, which is very important for safety. One of these plants is the fruit of the Spondias genus, which during its processing generates various residues that are discarded, but which also have pharmacological properties. The focus of this review is to survey the pharmacological activities that Spondias genus shows, as well as which part of the plant is used, since there is a lot of richness in its by-products, such as leaf, bark, resin, seed, and peel, which are discarded and could be reused. The main activities of this genus are antioxidant, anti-inflammatory, antidiabetic, antifungal, and antiviral, among others. These properties indicate that this genus could be used in the treatment of several diseases, but there are still not many products available on the market that use this genus as an active ingredient.

Keywords: Spondias; anti-inflammatory; antibacterial; antioxidant; bioactive compounds; biological activity.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Chemical structure of the main bioactive compounds of the Spondias genus. Figure was created by authors using ChemSketch 1.
See this image and copyright information in PMC

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